SCHEMBL22325673

SCHEMBL22325673

C1CCCC(C2CCCCCC2)CC1.CN=C=O

nearest known ligand 0.50

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.50
CASP1 P29466 1/20 0.50
ALDH1A1 P00352 2/20 0.46
EPHX1 P07099 1/20 0.32
HIF1A Q16665 1/20 0.32
SIGMAR1 Q99720 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29201843 0.85 TSHR (0.60) TSHRCASP1ALDH1A1
Cyclohexane SCHEMBL3761116 0.82 TSHR (0.75) TSHRCASP1ALDH1A1
Cyclohexane SCHEMBL1930585 0.82 TSHR (0.75) TSHRCASP1ALDH1A1
Cyclopropane SCHEMBL28687940 0.82
Cyclohexane SCHEMBL28947641 0.82 TSHR (0.75) TSHRCASP1ALDH1A1
Biphenyl SCHEMBL2988001 0.78 ALDH1A1 (0.73) ALDH1A1
Biphenyl SCHEMBL17459186 0.74 ALDH1A1 (0.42) ALDH1A1
Biphenyl SCHEMBL4048778 0.73 ALDH1A1 (0.53) ALDH1A1EPHX1HIF1A
Biphenyl SCHEMBL15309189 0.73 ALDH1A1 (0.53) ALDH1A1EPHX1HIF1A
SCHEMBL5201533 0.73 ALDH1A1 (0.53) ALDH1A1EPHX1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020162507-A1 CURABLE COMPOSITION サンスター技研株式会社 2020-08-13 WO disclosed