Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TLR4 | O00206 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22326031 | 0.95 | CYP19A1 (0.44) | CYP19A1CA12CA1CA2CA7 | |
| SCHEMBL22325742 | 0.90 | CYP19A1 (0.41) | CYP19A1CA12CA1CA2CA7 | |
| SCHEMBL22326022 | 0.87 | MAOB (0.47) | KMT2ANPC1RAB9AMAOBMEN1 | |
| SCHEMBL16738992 | 0.80 | MGMT (0.50) | CYP19A1CA12CA1CA2CA7 | |
| SCHEMBL22325743 | 0.77 | CYP19A1 (0.44) | CYP19A1CNR2KMT2ANPC1RAB9A | |
| SCHEMBL15774527 | 0.77 | HTT (0.46) | KMT2AMEN1MAPTLMNASMN1; SMN2 | |
| SCHEMBL29278446 | 0.75 | MAPT (0.44) | KMT2AMEN1MAPTLMNAMAPK1 | |
| SCHEMBL29056138 | 0.72 | CYP19A1 (0.45) | CYP19A1CNR2KMT2ANPC1RAB9A | |
| SCHEMBL29056136 | 0.70 | CYP19A1 (0.43) | CYP19A1CNR2KMT2ANPC1RAB9A | |
| SCHEMBL28095853 | 0.70 | MAPT (0.53) | CYP19A1CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020162471-A1 | PYRIDONE DERIVATIVE | マルホ株式会社 | 2020-08-13 | — | — | WO | disclosed |