Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | TLR4 | O00206 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22326031 | 0.81 | CYP19A1 (0.44) | CYP19A1KMT2AMAPTMEN1CRHBP | |
| SCHEMBL22326032 | 0.77 | CYP19A1 (0.41) | CYP19A1KMT2AMAPTMEN1CRHBP | |
| SCHEMBL22325742 | 0.76 | CYP19A1 (0.41) | CYP19A1KMT2AMAPTMEN1TLR4 | |
| SCHEMBL29056138 | 0.72 | CYP19A1 (0.45) | CYP19A1KMT2AMAPTMEN1CRHBP | |
| SCHEMBL2987569 | 0.71 | TLR4 (0.53) | CYP19A1KMT2AMAPTMEN1TLR4 | |
| SCHEMBL30510897 | 0.71 | CYP19A1 (0.43) | CYP19A1KMT2AMAPTMEN1CRHBP | |
| SCHEMBL26039527 | 0.71 | CYP19A1 (0.43) | CYP19A1KMT2AMAPTMEN1CRHBP | |
| SCHEMBL29056136 | 0.70 | CYP19A1 (0.43) | CYP19A1KMT2AMAPTMEN1CRHBP | |
| SCHEMBL25368475 | 0.69 | THRA (0.43) | CYP19A1KMT2AMAPTMEN1NPC1 | |
| SCHEMBL29056137 | 0.69 | CYP19A1 (0.40) | CYP19A1KMT2AMAPTMEN1CRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020162471-A1 | PYRIDONE DERIVATIVE | マルホ株式会社 | 2020-08-13 | — | — | WO | disclosed |