Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 5/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7641221 | 0.82 | CHRM2 (0.37) | CHRM1CHRM2HTR1AADRA2ADRD1 | |
| SCHEMBL9732815 | 0.81 | ANPEP (0.39) | CHRM1CHRM2HTR1AADRA2ADRD1 | |
| SCHEMBL29987214 | 0.81 | CHRM2 (0.36) | CHRM1CHRM2HTR1AADRA2ADRD1 | |
| SCHEMBL8895975 | 0.81 | CHRM2 (0.39) | CHRM1CHRM2HTR1AADRA2ADRD1 | |
| SCHEMBL6910045 | 0.81 | CHRM2 (0.36) | CHRM1CHRM2HTR1AADRA2ADRD1 | |
| SCHEMBL6251579 | 0.81 | CHRM2 (0.36) | CHRM1CHRM2HTR1AADRA2ADRD1 | |
| SCHEMBL6932058 | 0.81 | CHRM1 (0.39) | CHRM1CHRM2HTR1AADRA2ADRD1 | |
| Hydrochloric Acid SCHEMBL6250497 | 0.79 | CHRM1 (0.35) | CHRM1CHRM2HTR1AADRA2ADRD1 | |
| Hydrochloric Acid SCHEMBL17835959 | 0.79 | CHRM2 (0.35) | CHRM1CHRM2HTR1AADRA2ADRD1 | |
| Hydrochloric Acid SCHEMBL28374419 | 0.79 | CHRM2 (0.35) | CHRM1CHRM2HTR1AADRA2ADRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020103312-A1 | Asymmetric silicon-bridged metallocenes useful as catalysts in the polymerization of alpha-olefins, process for their preparation and use of said metallocenes for the polymerization of alpha-olefins | INNOVENE MANUFACTURING BELGIUM NV (BE) | 2002-08-01 | — | — | US | claimed |
| EP-1213295-A2 | Asymmetric silicon-bridged metallocenes useful as catalysts in the polymerization of Alpha-olefins, process for their preparation and use of said metallocenes for the polymerization of Alpha-olefins | Solvay Polyolefins Europe-Belgium (Société Anonyme) (BE) | 2002-06-12 | — | — | EP | claimed |
| US-8461270-B2 | Olefin/aromatic vinyl copolymer, process for production thereof, resin compositions containing the copolymer, and stretched products of the copolymer | IDEMITSU KOSAN CO., LTD. (JP) | 2013-06-11 | — | — | US | disclosed |
| EP-2157108-B1 | OLEFIN/AROMATIC VINYL COPOLYMER, PROCESS FOR PRODUCTION THEREOF, RESIN COMPOSITIONS CONTAINING THE COPOLYMER, AND STRETCHED PRODUCTS OF THE COPOLYMER | IDEMITSU KOSAN CO (JP) | 2013-02-20 | — | — | EP | disclosed |
| US-20110172366-A1 | OLEFIN/AROMATIC VINYL COPOLYMER, PROCESS FOR PRODUCTION THEREOF, RESIN COMPOSITIONS CONTAINING THE COPOLYMER, AND STRETCHED PRODUCTS OF THE COPOLYMER | IDEMITSU KOSAN CO., LTD. (JP) | 2011-07-14 | — | — | US | disclosed |
| CN-101796090-A | Copolymer comprising olefin and aromatic vinyl compound, process for producing the same, resin composition containing the copolymer, and stretched molded article of the copolymer | IDEMITSU KOSAN CO | 2010-08-04 | — | — | CN | disclosed |
| EP-2157108-A1 | OLEFIN/AROMATIC VINYL COPOLYMER, PROCESS FOR PRODUCTION THEREOF, RESIN COMPOSITIONS CONTAINING THE COPOLYMER, AND STRETCHED PRODUCTS OF THE COPOLYMER | Idemitsu Kosan Co., Ltd. (JP) | 2010-02-24 | — | — | EP | disclosed |
| US-6538082-B2 | With an indenyl and partially or fully hydrogenated fluorenyl group | SOLVAY POLYOLEFINS EUROPE-BELGIUM (BE) | 2003-03-25 | — | — | US | disclosed |
| US-20020103312-A1 | Asymmetric silicon-bridged metallocenes useful as catalysts in the polymerization of alpha-olefins, process for their preparation and use of said metallocenes for the polymerization of alpha-olefins | INNOVENE MANUFACTURING BELGIUM NV (BE) | 2002-08-01 | — | — | US | disclosed |
| EP-1213295-A2 | Asymmetric silicon-bridged metallocenes useful as catalysts in the polymerization of Alpha-olefins, process for their preparation and use of said metallocenes for the polymerization of Alpha-olefins | Solvay Polyolefins Europe-Belgium (Société Anonyme) (BE) | 2002-06-12 | — | — | EP | disclosed |
| US-5670680-A | Method for producing octahydrofluorenyl metal complexes | THE DOW CHEMICAL COMPANY (US) | 1997-09-23 | — | — | US | disclosed |