SCHEMBL6932058

SCHEMBL6932058

CC1CCCC2=C1Cc1ccccc12

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 4/20 0.39
CHRM2 P08172 1/20 0.39
HTR1A P08908 1/20 0.39
ADRA2A P08913 1/20 0.39
DRD1 P21728 1/20 0.39
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
ADRA1A P35348 1/20 0.39
OPRM1 P35372 1/20 0.39
DRD3 P35462 1/20 0.39
SLC6A3 Q01959 1/20 0.39
KCNH2 Q12809 1/20 0.39
ACHE P22303 2/20 0.37
PGR P06401 1/20 0.35
MAOA P21397 1/20 0.34
IDO1 P14902 2/20 0.34
TSHR P16473 1/20 0.34
HRH3 Q9Y5N1 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
BCHE P06276 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28827695 0.82 IDO1 (0.38) CHRM1CHRM2HTR1AADRA2ADRD1
SCHEMBL61050 0.81 CHRM1 (0.38) CHRM1CHRM2HTR1AADRA2ADRD1
SCHEMBL2232626 0.81 CHRM1 (0.37) CHRM1CHRM2HTR1AADRA2ADRD1
SCHEMBL7641221 0.81 CHRM2 (0.37) CHRM1CHRM2HTR1AADRA2ADRD1
SCHEMBL7549766 0.80 CHRM1 (0.37) CHRM1CHRM2HTR1AADRA2ADRD1
SCHEMBL31039630 0.80 CHRM1 (0.37) CHRM1CHRM2HTR1AADRA2ADRD1
SCHEMBL6251442 0.80 CHRM1 (0.37) CHRM1CHRM2HTR1AADRA2ADRD1
SCHEMBL3824348 0.80 CHRM1 (0.35) CHRM1CHRM2HTR1AADRA2ADRD1
SCHEMBL29987214 0.79 CHRM2 (0.36) CHRM1CHRM2HTR1AADRA2ADRD1
SCHEMBL6910045 0.79 CHRM2 (0.36) CHRM1CHRM2HTR1AADRA2ADRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119751511-A Transition metal carbene catalyst, preparation method and application thereof 杭州睿丰融创科技有限公司 2025-04-04 CN claimed
CN-119751511-A Transition metal carbene catalyst, preparation method and application thereof 杭州睿丰融创科技有限公司 2025-04-04 CN disclosed
CN-118974160-A Cyclic olefin resin composition, varnish, crosslinked material, film, sheet, circuit board, electronic device, and prepreg 三井化学株式会社 2024-11-15 CN disclosed
CN-118159582-A Polymer, method for producing same, resin composition, and electronic component 日本瑞翁株式会社 2024-06-07 CN disclosed
CN-112703435-B Optical film, method for producing same, optical laminate, and liquid crystal display device 日本瑞翁株式会社 2023-03-24 CN disclosed
CN-113286705-B Optical film, polarizing plate and image display device 日本瑞翁株式会社 2023-03-10 CN disclosed
CN-115605425-A Micro-channel chip and manufacturing method thereof 日本瑞翁株式会社(JP) 2023-01-13 CN disclosed
CN-114980851-A Pre-filled medicament package and method of manufacturing a pre-filled medicament package 日本瑞翁株式会社 2022-08-30 CN disclosed
CN-114729132-A Resin composition, molded article obtained by molding same, and method for producing resin composition 日本瑞翁株式会社 2022-07-08 CN disclosed
CN-114126865-A Multilayer film, method for producing same, and wound body 日本瑞翁株式会社 2022-03-01 CN disclosed
CN-111247463-A Polarizing film and method for producing same 日本瑞翁株式会社 2020-06-05 CN disclosed
CN-111132828-A Optical laminated film and touch panel 日本瑞翁株式会社 2020-05-08 CN disclosed
CN-108698389-B Multilayer film and method of manufacture 日本瑞翁株式会社 2020-04-28 CN disclosed
CN-106661247-B Method for producing cut optical film 日本瑞翁株式会社 2020-03-20 CN disclosed
CN-107315216-B Phase difference film 日本瑞翁株式会社 2020-02-04 CN disclosed
CN-107250262-B Resin composition and resin molded article 日本瑞翁株式会社 2019-12-20 CN disclosed
EP-1120389-B1 Preparation process of fluorenes JFE CHEMICAL CORP (JP) 2003-11-26 EP disclosed
US-6344585-B2 DEHYDROGENATION OF THE CORRESPONDING TETRAHYDROFLUORENECOMPOUND ADCHEMCO CORPORATION (JP) 2002-02-05 US disclosed
US-20010011144-A1 Preparation process of fluorenes ADCHEMCO CORPORATION (JP) 2001-08-02 US disclosed
EP-1120389-A1 Preparation process of fluorenes Adchemco Corporation (JP) 2001-08-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010011144-A1 Preparation process of fluorenes AFF1, NAF1, RER1 CHRM1 1209/4885CHRM2 2866/4885HTR1A 270/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.