Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.41 |
| ▸ | RELA | Q04206 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7648229 | 0.89 | CYP1A2 (0.44) | LMNATBXAS1KCNA5L3MBTL1TDP1 | |
| SCHEMBL3664564 | 0.84 | CYP1A2 (0.46) | CYP1A2HTTALDH1A1 | |
| SCHEMBL28416200 | 0.84 | CYP1A2 (0.46) | CYP1A2HTTALDH1A1 | |
| SCHEMBL28419010 | 0.84 | CYP1A2 (0.46) | CYP1A2HTTALDH1A1 | |
| SCHEMBL28419024 | 0.84 | CYP1A2 (0.46) | CYP1A2HTTALDH1A1 | |
| SCHEMBL3664383 | 0.84 | CYP1A2 (0.46) | CYP1A2HTTALDH1A1 | |
| SCHEMBL16586535 | 0.82 | CYP1A2 (0.47) | MAPTCYP1A2ALDH1A1 | |
| SCHEMBL27672756 | 0.79 | CNR1 (0.50) | CNR1CNR2LMNAPOLBKCNA5 | |
| SCHEMBL372366 | 0.78 | KIF11 (0.49) | L3MBTL1TDP1MAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL11632766 | 0.77 | KCNA5 (0.51) | CNR1CNR2LMNAPOLBKCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020162725-A1 | TARGET PROTEIN EED DEGRADATION-INDUCING DEGRADUCER, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING DISEASES RELATED TO EED, EZH2, OR PRC2, COMPRISING SAME AS ACTIVE INGREDIENT | 한국화학연구원 | 2020-08-13 | — | — | WO | disclosed |