Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 6/20 | 0.54 |
| ▸ | OXTR | P30559 | 1/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.49 |
| ▸ | ITGAV | P06756 | 1/20 | 0.49 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.49 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.48 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.47 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22292162 | 1.00 | HDAC4 (0.54) | HDAC4OXTRITGB3ITGB1ITGAV | |
| SCHEMBL21164408 | 0.97 | OXTR (0.52) | HDAC4OXTRITGB3ITGB1ITGAV | |
| SCHEMBL22326367 | 0.97 | OXTR (0.53) | HDAC4OXTRITGB3ITGB1ITGAV | |
| SCHEMBL22326368 | 0.97 | OXTR (0.53) | HDAC4OXTRITGB3ITGB1ITGAV | |
| SCHEMBL22326376 | 0.97 | HDAC4 (0.52) | HDAC4OXTRITGB3ITGB1ITGAV | |
| SCHEMBL22326373 | 0.96 | HDAC4 (0.57) | HDAC4OXTRITGB3ITGB1ITGAV | |
| SCHEMBL21164405 | 0.94 | OXTR (0.54) | HDAC4OXTRITGB3ITGB1ITGAV | |
| SCHEMBL22292134 | 0.94 | OXTR (0.56) | HDAC4OXTRITGB3ITGB1ITGAV | |
| SCHEMBL22326371 | 0.94 | OXTR (0.53) | HDAC4OXTRITGB3ITGB1ITGAV | |
| SCHEMBL21164373 | 0.94 | OXTR (0.53) | HDAC4OXTRITGB3ITGB1ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10738085-B1 | Antimicrobial analogues of Gramicidin S | UNIVERSITY OF SOUTH FLORIDA (US) | 2020-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10738085-B1 | Antimicrobial analogues of Gramicidin S | GMPS, AAAS, GNPDA1 | HDAC4 2862/4885OXTR 3605/4885ITGB3 3078/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.