SCHEMBL2232657

SCHEMBL2232657

C=CC(=O)OC(COCC)OCC

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.40
HPGD P15428 1/20 0.35
ALDH1A1 P00352 4/20 0.34
TP53 P04637 2/20 0.34
HIF1A Q16665 2/20 0.34
HSD17B10 Q99714 1/20 0.34
THRB P10828 2/20 0.33
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27405537 0.88 TSHR (0.40) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL183146 0.87 TSHR (0.42) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL4080187 0.84 TSHR (0.40) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL6909240 0.84 TSHR (0.40) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL237171 0.83 TSHR (0.39) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL8988187 0.81 TSHR (0.38) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28059039 0.81 TSHR (0.38) TSHRHPGDALDH1A1TP53HIF1A
Acrylic Acid SCHEMBL7265241 0.81 LMNA (0.39) TSHRALDH1A1HSD17B10
Ethylene Glycol SCHEMBL2381774 0.81 TSHR (0.49) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL16260091 0.81 TSHR (0.41) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8012667-B2 Soft mold and method of fabricating the same LG DISPLAY CO. LTD. (KR) 2011-09-06 US claimed
US-20080044743-A1 Soft mold and method of fabricating the same LG PHILIPS LCD., LTD. 2008-02-21 US claimed
US-8012667-B2 Soft mold and method of fabricating the same LG DISPLAY CO. LTD. (KR) 2011-09-06 US disclosed
US-20110172330-A1 POLYPROPYLENE OXIDE-CONTAINING POLYETHERS AND MIXTURES THEREOF WITH POLY(METH)ACRYLATES AS POWDER COATING LEVELING AGENTS BYK-CHEMIE GMBH (DE) 2011-07-14 US disclosed
US-20080044743-A1 Soft mold and method of fabricating the same LG PHILIPS LCD., LTD. 2008-02-21 US disclosed
EP-1234681-B1 Reversible thermosensitive recording medium and image processing method using the same RICOH KK (JP) 2007-04-18 EP disclosed
US-6777458-B1 ACRYLIC RESIN COATING IS CURED BY EXPOSURE TO UV RADIATION IS FLUSHED WITH A PROTECTIVE GAS BASF AKTIENGESELLSCHAFT (DE) 2004-08-17 US disclosed
US-6770592-B2 Reversible thermosensitive recording medium and image processing method using the same RICOH COMPANY, LTD. (JP) 2004-08-03 US disclosed
US-20030092571-A1 Reversible thermosensitive recording medium and image processing method using the same RIOCH COMPANY, LTD. (JP) 2003-05-15 US disclosed
EP-1234681-A1 Reversible thermosensitive recording medium and image processing method using the same Ricoh Company, Ltd. (JP) 2002-08-28 EP disclosed
US-6106940-A ADHESIVE POLYMER AND AS A TACKIFIER OR PLASTICIZER, A ZWITTERIONIC COMPOUND SUCH AS N-(2-HYDROXY-3-SULFOPROPYL)-N,N-DIMETHYL-N-(3-BUTYLOXY-2-HYDROXYPROPYL) -AMMONIUM BETAINE; ADHESIVE TAPES 3M INNOVATIVE PROPERTIES COMPANY (US) 2000-08-22 US disclosed
US-5743981-A Optical security articles and methods for making same MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-04-28 US disclosed