Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 4/20 | 0.48 |
| ▸ | CCR5 | P51681 | 4/20 | 0.48 |
| ▸ | CCR8 | P51685 | 4/20 | 0.48 |
| ▸ | TET2 | Q6N021 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22326640 | 0.88 | CCR1 (0.45) | CCR1CCR5CCR8TET2KDM4E | |
| SCHEMBL24716089 | 0.85 | KDM4E (0.51) | CCR1CCR5CCR8KDM4EPSMD14 | |
| SCHEMBL737261 | 0.85 | CCR1 (0.42) | CCR1CCR5CCR8TET2KDM4E | |
| SCHEMBL24715871 | 0.82 | CCR1 (0.40) | CCR1CCR5CCR8 | |
| SCHEMBL737118 | 0.81 | CCR1 (0.39) | CCR1CCR5CCR8KDM4EPSMD14 | |
| SCHEMBL27692215 | 0.81 | CCR1 (0.39) | CCR1CCR5CCR8KDM4EPSMD14 | |
| SCHEMBL18710738 | 0.79 | KDM4E (0.40) | CCR1CCR5CCR8TET2KDM4E | |
| SCHEMBL26239496 | 0.78 | TET2 (0.69) | CCR1CCR5CCR8TET2KDM4E | |
| SCHEMBL21988834 | 0.75 | TET2 (0.42) | TET2KDM4EPARP1 | |
| SCHEMBL22326638 | 0.75 | TET2 (0.63) | TET2KDM4EPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11219214-B2 | Benzosultams and analogues and their use as fungicides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2022-01-11 | — | — | US | disclosed |
| WO-2021138450-A1 | NOVEL SMALL MOLECULE SHC BLOCKERS FOR TREATING LIVER DISEASE AND METABOLIC DISEASE | BUTO CORPORATION (US) | 2021-07-08 | — | — | WO | disclosed |
| US-20200323211-A1 | BENZOSULTAMS AND ANALOGUES AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-10-15 | — | — | US | disclosed |
| US-10736321-B2 | Benzosultams and analogues and their use as fungicides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200323211-A1 | BENZOSULTAMS AND ANALOGUES AND THEIR USE AS FUNGICIDES | GABBR1, DPM1, CYP51A1 | CCR1 4876/4885CCR5 4873/4885CCR8 4830/4885 |
| US-10736321-B2 | Benzosultams and analogues and their use as fungicides | GABBR1, DPM1, CYP51A1 | CCR1 4876/4885CCR5 4873/4885CCR8 4830/4885 |
| US-11219214-B2 | Benzosultams and analogues and their use as fungicides | GABBR1, DPM1, CYP51A1 | CCR1 4876/4885CCR5 4873/4885CCR8 4830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.