SCHEMBL26239496

SCHEMBL26239496

Cc1cnc2c(F)ccc(S(=O)(=O)O)c2c1

nearest known ligand 0.69

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 4/20 0.69
SLC40A1 Q9NP59 3/20 0.42
COMT P21964 2/20 0.38
CCR1 P32246 1/20 0.37
CCR5 P51681 1/20 0.37
CCR8 P51685 1/20 0.37
ALDH1A1 P00352 1/20 0.36
CYP1A2 P05177 1/20 0.36
ALOX15 P16050 1/20 0.36
HIF1A Q16665 1/20 0.36
HSD17B10 Q99714 1/20 0.36
GRM5 P41594 4/20 0.36
CYP2C19 P33261 1/20 0.35
KDM4E B2RXH2 1/20 0.34
PARP1 P09874 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24715819 0.83 COMT (0.56) TET2COMTCCR1CCR5CCR8
SCHEMBL22723686 0.79 TET2 (0.66) TET2COMTALDH1A1CYP1A2ALOX15
SCHEMBL22326641 0.78 CCR1 (0.48) TET2SLC40A1CCR1CCR5CCR8
SCHEMBL22326640 0.75 CCR1 (0.45) TET2SLC40A1CCR1CCR5CCR8
SCHEMBL9346839 0.73 COMT (0.69) TET2COMTALDH1A1CYP1A2ALOX15
SCHEMBL11161309 0.72 TTR (0.45) TET2COMTALDH1A1CYP1A2ALOX15
SCHEMBL18710738 0.71 KDM4E (0.40) TET2CCR1CCR5CCR8ALDH1A1
SCHEMBL24716089 0.69 KDM4E (0.51) COMTCCR1CCR5CCR8ALDH1A1
SCHEMBL2997901 0.69 KDM4E (0.58) SLC40A1CCR1CCR5CCR8ALDH1A1
SCHEMBL24715821 0.69 ALDH1A1 (0.46) ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11754927-B2 Photoresist pattern trimming compositions and pattern formation methods ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2023-09-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11754927-B2 Photoresist pattern trimming compositions and pattern formation methods AHR, ALKBH1, CNOT1 TET2 361/4885SLC40A1 3947/4885COMT 4486/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.