Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASEL | Q05823 | 10/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.51 |
| ▸ | TGM2 | P21980 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22326788 | 0.93 | RNASEL (0.62) | RNASELADORA1 | |
| SCHEMBL22326712 | 0.93 | RNASEL (0.62) | RNASELADORA1 | |
| SCHEMBL27273378 | 0.92 | RNASEL (0.52) | RNASELADORA1 | |
| SCHEMBL18521014 | 0.91 | POLB (0.58) | RNASEL | |
| SCHEMBL18510903 | 0.91 | POLB (0.58) | RNASEL | |
| SCHEMBL18521007 | 0.91 | POLB (0.58) | RNASEL | |
| SCHEMBL22326713 | 0.90 | RNASEL (0.66) | RNASEL | |
| SCHEMBL18510904 | 0.90 | RNASEL (0.60) | RNASEL | |
| SCHEMBL18521632 | 0.90 | RNASEL (0.60) | RNASEL | |
| SCHEMBL18521011 | 0.90 | RNASEL (0.60) | RNASEL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10738074-B2 | Cyclic di-nucleotide compounds as STING agonists | MERCK SHARP & DOHME CORP. (US) | 2020-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10738074-B2 | Cyclic di-nucleotide compounds as STING agonists | STING1, CGAS, IFNAR1 | RNASEL 555/4885ADORA1 36/4885TGM2 3085/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.