Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.55 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.55 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.55 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.54 |
| ▸ | TGM2 | P21980 | 1/20 | 0.50 |
| ▸ | KRAS | P01116 | 2/20 | 0.48 |
| ▸ | POLG | P54098 | 1/20 | 0.46 |
| ▸ | P2RY1 | P47900 | 3/20 | 0.46 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.46 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.46 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.46 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.46 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.46 |
| ▸ | NT5E | P21589 | 1/20 | 0.46 |
| ▸ | PNP | P00491 | 1/20 | 0.45 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.45 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26068895 | 1.00 | POLB (0.58) | POLBP2RY6P2RY2P2RY4FUT5 | |
| SCHEMBL22327359 | 1.00 | POLB (0.58) | POLBP2RY6P2RY2P2RY4FUT5 | |
| SCHEMBL26068898 | 1.00 | POLB (0.58) | POLBP2RY6P2RY2P2RY4FUT5 | |
| SCHEMBL24370821 | 0.87 | POLB (0.65) | POLBP2RY6P2RY2P2RY4FUT5 | |
| SCHEMBL25070778 | 0.87 | POLB (0.65) | POLBP2RY6P2RY2P2RY4FUT5 | |
| SCHEMBL27102634 | 0.87 | POLB (0.65) | POLBP2RY6P2RY2P2RY4FUT5 | |
| SCHEMBL19175178 | 0.87 | POLB (0.59) | POLBP2RY6P2RY2P2RY4FUT5 | |
| SCHEMBL18844553 | 0.87 | POLB (0.59) | POLBP2RY6P2RY2P2RY4FUT5 | |
| SCHEMBL24895768 | 0.87 | POLB (0.59) | POLBP2RY6P2RY2P2RY4FUT5 | |
| SCHEMBL18844550 | 0.87 | POLB (0.59) | POLBP2RY6P2RY2P2RY4FUT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230257414-A1 | NUCLEOTIDE ANALOGUES | FIRST-CITIZENS BANK & TRUST COMPANY | 2023-08-17 | — | — | US | disclosed |
| US-20230257414-A1 | NUCLEOTIDE ANALOGUES | FIRST-CITIZENS BANK & TRUST COMPANY | 2023-08-17 | — | — | US | disclosed |
| US-20220127299-A1 | NUCLEOTIDE CLEAVABLE LINKERS AND USES THEREOF | LG ELECTRONICS INC. (KR) | 2022-04-28 | — | — | US | disclosed |
| US-10822653-B1 | Nucleotide cleavable linkers and uses thereof | Singular Genomics Systems, Inc. (US) | 2020-11-03 | — | — | US | disclosed |
| US-20200340051-A1 | NUCLEOTIDE CLEAVABLE LINKERS AND USES THEREOF | FIRST-CITIZENS BANK & TRUST COMPANY | 2020-10-29 | — | — | US | disclosed |
| US-10738072-B1 | Nucleotide analogues | Singular Genomics Systems, Inc. (US) | 2020-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200340051-A1 | NUCLEOTIDE CLEAVABLE LINKERS AND USES THEREOF | NUDT21, CPSF7, DCLRE1A | POLB 24/4885P2RY6 3127/4885P2RY2 3976/4885 |
| US-20220127299-A1 | NUCLEOTIDE CLEAVABLE LINKERS AND USES THEREOF | NUDT21, CPSF7, DCLRE1A | POLB 24/4885P2RY6 3127/4885P2RY2 3976/4885 |
| US-20230257414-A1 | NUCLEOTIDE ANALOGUES | ITPA, POLB, NUDT1 | POLB 2/4885P2RY6 948/4885P2RY2 1336/4885 |
| US-10822653-B1 | Nucleotide cleavable linkers and uses thereof | NUDT21, CPSF7, DCLRE1A | POLB 24/4885P2RY6 3127/4885P2RY2 3976/4885 |
| US-10738072-B1 | Nucleotide analogues | NUDT1, POLN, TYMP | POLB 12/4885P2RY6 832/4885P2RY2 1236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.