Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 2/20 | 0.81 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.77 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.77 |
| ▸ | AKT1 | P31749 | 1/20 | 0.77 |
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.39 |
| ▸ | HTR3A | P46098 | 3/20 | 0.38 |
| ▸ | ELF3 | P78545 | 2/20 | 0.37 |
| ▸ | MED23 | Q9ULK4 | 2/20 | 0.37 |
| ▸ | TSG101 | Q99816 | 3/20 | 0.36 |
| ▸ | HTRA2 | O43464 | 1/20 | 0.36 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22730942 | 1.00 | PTGER2 (0.81) | PTGER2EPHA2NFKBIAAKT1EGFR | |
| SCHEMBL22328123 | 0.96 | PTGER2 (0.74) | PTGER2EPHA2NFKBIAAKT1EGFR | |
| SCHEMBL22328139 | 0.94 | PTGER2 (0.81) | PTGER2EPHA2NFKBIAAKT1EGFR | |
| SCHEMBL22328142 | 0.94 | PTGER2 (0.74) | PTGER2EPHA2NFKBIAAKT1EGFR | |
| SCHEMBL22328141 | 0.87 | EPHA2 (0.83) | PTGER2EPHA2NFKBIAAKT1EGFR | |
| SCHEMBL22328134 | 0.87 | EPHA2 (1.00) | PTGER2EPHA2NFKBIAAKT1EGFR | |
| SCHEMBL22328137 | 0.85 | EPHA2 (0.91) | PTGER2EPHA2NFKBIAAKT1EGFR | |
| SCHEMBL22730944 | 0.79 | EPHA2 (0.65) | PTGER2EPHA2NFKBIAAKT1EGFR | |
| SCHEMBL23598422 | 0.69 | PTGER2 (0.66) | PTGER2EPHA2NFKBIAAKT1EGFR | |
| SCHEMBL23598456 | 0.69 | PTGER2 (0.69) | PTGER2EPHA2NFKBIAAKT1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10738082-B2 | One-bead-two-compound macrocyclic library and methods of preparation and use | UNIVERSITY OF SOUTH FLORIDA (US) | 2020-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10738082-B2 | One-bead-two-compound macrocyclic library and methods of preparation and use | EPHA2, EPHA1, EPHB2 | PTGER2 187/4885EPHA2 1/4885NFKBIA 3054/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.