Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CDK9 | P50750 | 1/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18415224 | 0.91 | SMN1; SMN2 (0.53) | SMN1; SMN2TP53EPHX2EPHX1TSHR | |
| SCHEMBL18236215 | 0.78 | SMN1; SMN2 (0.61) | SMN1; SMN2TP53EPHX2EPHX1TSHR | |
| SCHEMBL18233027 | 0.73 | MAPK14 (0.54) | SMN1; SMN2TP53EPHX2EPHX1TSHR | |
| SCHEMBL23719154 | 0.72 | TP53 (0.57) | SMN1; SMN2TP53EPHX2EPHX1TSHR | |
| Diphenylurea SCHEMBL133103 | 0.71 | SMN1; SMN2 (1.00) | SMN1; SMN2TP53EPHX2EPHX1TSHR | |
| SCHEMBL20804375 | 0.69 | SMN1; SMN2 (0.85) | SMN1; SMN2TP53EPHX2EPHX1TSHR | |
| Diphenylurea SCHEMBL29392345 | 0.69 | SMN1; SMN2 (0.94) | SMN1; SMN2TP53EPHX2EPHX1TSHR | |
| Diphenylurea SCHEMBL3037927 | 0.69 | SMN1; SMN2 (0.94) | SMN1; SMN2TP53EPHX2EPHX1TSHR | |
| Diphenylurea SCHEMBL30786615 | 0.69 | SMN1; SMN2 (0.94) | SMN1; SMN2TP53EPHX2EPHX1TSHR | |
| Diphenylurea SCHEMBL28431956 | 0.69 | SMN1; SMN2 (0.94) | SMN1; SMN2TP53EPHX2EPHX1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10738035-B2 | Hepatitis B antiviral agents | ENANTA PHARMACEUTICALS, INC. (US) | 2020-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10738035-B2 | Hepatitis B antiviral agents | ZC3HAV1, ZC3HAV1L, HAVCR2 | SMN1; SMN2 4775/4885TP53 1448/4885EPHX2 3447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.