Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.54 |
| ▸ | DGKA | P23743 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | POLA1 | P09884 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8123044 | 0.98 | TSHR (0.56) | TSHRDGKAMEN1THRBHTT | |
| SCHEMBL17908707 | 0.94 | TSHR (0.56) | TSHRDGKAMEN1THRBHTT | |
| SCHEMBL17909620 | 0.94 | TSHR (0.56) | TSHRDGKAMEN1THRBHTT | |
| SCHEMBL17909429 | 0.94 | TSHR (0.56) | TSHRDGKAMEN1THRBHTT | |
| SCHEMBL17909460 | 0.92 | TSHR (0.54) | TSHRDGKAMEN1THRBHTT | |
| SCHEMBL14424555 | 0.92 | DGKA (0.59) | TSHRDGKAMEN1THRBHTT | |
| SCHEMBL17909434 | 0.92 | TSHR (0.54) | TSHRDGKAMEN1THRBHTT | |
| SCHEMBL17908976 | 0.92 | TSHR (0.54) | TSHRDGKAMEN1THRBHTT | |
| SCHEMBL10286759 | 0.92 | TSHR (0.58) | TSHRDGKAHTTKMT2AMAPT | |
| SCHEMBL17909213 | 0.90 | MEN1 (0.53) | TSHRDGKAMEN1THRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305784-B1 | HAPTENS OF QUETIAPINE FOR USE IN IMMUNOASSAYS | JANSSEN PHARMACEUTICA NV (BE) | 2020-08-12 | — | — | EP | disclosed |