SCHEMBL22329677

SCHEMBL22329677

c1ccc(-c2cccc(-c3nc(-c4ccccc4)nc(-c4cccc5c4oc4cccc(-c6nc(-c7ccccc7)nc(-c7cccc8c7sc7ccccc78)n6)c45)n3)c2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.38
PRKDC P78527 9/20 0.38
PIK3CD O00329 2/20 0.38
PIK3CB P42338 2/20 0.38
BRD4 O60885 1/20 0.36
PIK3CA P42336 1/20 0.36
MTOR P42345 1/20 0.36
PIK3CG P48736 1/20 0.36
KCNH2 Q12809 1/20 0.36
BRDT Q58F21 1/20 0.36
MAPT P10636 2/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
POLB P06746 1/20 0.33
NPSR1 Q6W5P4 1/20 0.32
ESR2 Q92731 2/20 0.32
ESR1 P03372 1/20 0.32
PARP14 Q460N5 1/20 0.32
LIMK1 P53667 1/20 0.32
TNKS O95271 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26051186 0.96 ALOX5 (0.38) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL25631384 0.96 ALOX5 (0.38) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL24217208 0.96 PRKDC (0.42) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL24216481 0.96 PRKDC (0.40) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL25627804 0.96 ALOX5 (0.40) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL22248748 0.95 ALOX5 (0.43) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL22329580 0.95 PRKDC (0.41) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL22330106 0.95 PRKDC (0.41) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL25627795 0.94 PRKDC (0.40) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL24215853 0.93 ALOX5 (0.40) ALOX5PRKDCPIK3CDPIK3CBBRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11581494-B2 Organic light emitting device LG CHEM, LTD. (KR) 2023-02-14 US disclosed
US-20200259098-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2020-08-13 US disclosed