SCHEMBL22329863

SCHEMBL22329863

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4cccc5c4oc4ccc(-c6nc(-c7ccccc7)nc(-c7ccccc7)n6)cc45)cc3)n2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.49
MAPT P10636 6/20 0.41
ALDH1A1 P00352 4/20 0.41
PTPRF P10586 4/20 0.41
PTPN2 P17706 4/20 0.41
PTPN1 P18031 4/20 0.41
KDM4E B2RXH2 4/20 0.41
HPGD P15428 3/20 0.41
POLB P06746 1/20 0.41
PIM1 P11309 1/20 0.40
CSNK2A2 P19784 1/20 0.40
CSNK2B P67870 1/20 0.40
PIM3 Q86V86 1/20 0.40
PIM2 Q9P1W9 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
GGPS1 O95749 1/20 0.39
TSHR P16473 4/20 0.39
HSD17B10 Q99714 3/20 0.39
MAPK1 P28482 2/20 0.39
TP53 P04637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22883912 1.00 ALOX5 (0.49) ALOX5MAPTALDH1A1PTPRFPTPN2
SCHEMBL17425607 1.00 ALOX5 (0.49) ALOX5MAPTALDH1A1PTPRFPTPN2
SCHEMBL21108986 0.99 ALOX5 (0.48) ALOX5MAPTALDH1A1PTPRFPTPN2
SCHEMBL24217344 0.99 ALOX5 (0.48) ALOX5MAPTALDH1A1PTPRFPTPN2
SCHEMBL20739795 0.99 ALOX5 (0.48) ALOX5MAPTALDH1A1PTPRFPTPN2
SCHEMBL24525959 0.99 ALOX5 (0.48) ALOX5MAPTALDH1A1PTPRFPTPN2
SCHEMBL24216934 0.99 ALOX5 (0.48) ALOX5MAPTALDH1A1PTPRFPTPN2
SCHEMBL24526098 0.99 ALOX5 (0.48) ALOX5MAPTALDH1A1PTPRFPTPN2
SCHEMBL24216541 0.99 ALOX5 (0.48) ALOX5MAPTALDH1A1PTPRFPTPN2
SCHEMBL25645823 0.99 ALOX5 (0.48) ALOX5MAPTALDH1A1PTPRFPTPN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11581494-B2 Organic light emitting device LG CHEM, LTD. (KR) 2023-02-14 US disclosed
US-20200259098-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2020-08-13 US disclosed