SCHEMBL22330141

SCHEMBL22330141

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc4oc5c(-c6nc(-c7ccccc7)nc(-c7ccc8c9ccccc9n(-c9ccccc9)c8c7)n6)cccc5c4c3)n2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ALOX5 P09917 2/20 0.36
SIRT2 Q8IXJ6 1/20 0.35
SIRT1 Q96EB6 1/20 0.35
PTPRF P10586 7/20 0.33
PTPN2 P17706 7/20 0.33
PTPN1 P18031 7/20 0.33
MAPT P10636 3/20 0.33
TSHR P16473 2/20 0.33
PIM1 P11309 1/20 0.33
CSNK2A2 P19784 1/20 0.33
CSNK2B P67870 1/20 0.33
PIM3 Q86V86 1/20 0.33
PIM2 Q9P1W9 1/20 0.33
LMNA P02545 1/20 0.33
MAPK1 P28482 1/20 0.33
HSD17B10 Q99714 1/20 0.33
ALDH1A1 P00352 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20754048 0.98 KDM4E (0.38) KDM4EATML3MBTL1ALOX5SIRT2
SCHEMBL23947791 0.97 ALOX5 (0.38) KDM4EATML3MBTL1ALOX5SIRT2
SCHEMBL23947790 0.96 ALOX5 (0.42) KDM4EATML3MBTL1ALOX5SIRT2
SCHEMBL21192090 0.96 ALOX5 (0.39) KDM4EATML3MBTL1ALOX5SIRT2
SCHEMBL22257883 0.96 ALOX5 (0.40) KDM4EATML3MBTL1ALOX5SIRT2
SCHEMBL23947998 0.95 ALOX5 (0.37) KDM4EATML3MBTL1ALOX5SIRT2
SCHEMBL23947794 0.95 ALOX5 (0.37) KDM4EATML3MBTL1ALOX5SIRT2
SCHEMBL22258056 0.95 PIM1 (0.36) KDM4EATML3MBTL1ALOX5SIRT2
SCHEMBL16810881 0.95 ALOX5 (0.41) KDM4EATML3MBTL1ALOX5MAPT
SCHEMBL22330144 0.95 ALOX5 (0.38) KDM4EATML3MBTL1ALOX5SIRT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11581494-B2 Organic light emitting device LG CHEM, LTD. (KR) 2023-02-14 US disclosed
US-20200259098-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2020-08-13 US disclosed