Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.48 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.48 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4394078 | 0.86 | CA1 (0.48) | HSP90AA1KMT2AMAPTTP53SMN1; SMN2 | |
| SCHEMBL4396935 | 0.85 | CELA1 (0.51) | HSP90AA1HSP90AB1PDK1KMT2AMAPT | |
| SCHEMBL2948885 | 0.78 | ALDH1A1 (0.57) | MAOBKMT2AMAPTTP53SMN1; SMN2 | |
| SCHEMBL3089612 | 0.72 | ALDH1A1 (0.54) | HSP90AA1KMT2AMAPTTP53SMN1; SMN2 | |
| SCHEMBL3096814 | 0.72 | ALDH1A1 (0.58) | HSP90AA1KMT2AMAPTTP53SMN1; SMN2 | |
| SCHEMBL5270355 | 0.71 | KDM4E (0.65) | KMT2AMAPTTP53SMN1; SMN2KDM4E | |
| SCHEMBL16698022 | 0.70 | KDM4E (0.67) | MAOBKMT2AMAPTTP53SMN1; SMN2 | |
| SCHEMBL2944800 | 0.70 | ALDH1A1 (0.68) | MAOBKMT2AMAPTTP53SMN1; SMN2 | |
| SCHEMBL22331074 | 0.69 | HSP90AA1 (0.77) | HSP90AA1HSP90AB1PDK1 | |
| SCHEMBL11550681 | 0.69 | ALDH1A1 (0.70) | KMT2AMAPTTP53SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10744213-B2 | Fluorescent compounds for imaging of blood vessels and blood flow, and an in vivo screen for pro- and anti-angiogenic agents | COLOSSUS BIOPHARMA CONSULTANTS COMPANY, LIMITED (TW) | 2020-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10744213-B2 | Fluorescent compounds for imaging of blood vessels and blood flow, and an in vivo screen for pro- and anti-angiogenic agents | FLT4, VEGFA, FLT1 | HSP90AA1 2235/4885HSP90AB1 2342/4885PDK1 4066/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.