SCHEMBL223314

SCHEMBL223314

COc1ccc(O)c(C(C)c2ccccc2)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 2/20 0.51
CYP2D6 P10635 3/20 0.51
CYP1A2 P05177 2/20 0.51
CYP2C19 P33261 2/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2C9 P11712 1/20 0.51
ALOX15 P16050 1/20 0.51
BCHE P06276 1/20 0.46
ACHE P22303 1/20 0.46
MAPT P10636 3/20 0.43
GAA P10253 3/20 0.43
TDP2 O95551 1/20 0.43
POLB P06746 1/20 0.43
ALDH1A1 P00352 5/20 0.43
KDM4E B2RXH2 3/20 0.43
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
THRB P10828 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL51662 0.86 GAA (0.52) TYRCYP2D6CYP1A2CYP2C19CYP3A4
SCHEMBL51818 0.85 MAPT (0.51) TYRCYP2D6CYP1A2CYP2C19CYP3A4
SCHEMBL28475878 0.85 MAPT (0.51) TYRCYP2D6CYP1A2CYP2C19CYP3A4
SCHEMBL29048103 0.83 BCHE (0.46) TYRCYP2D6CYP1A2CYP2C19CYP3A4
SCHEMBL11795944 0.82 BCHE (0.58) TYRCYP2D6CYP1A2CYP2C19CYP3A4
SCHEMBL4670011 0.81 CYP2D6 (0.56) CYP2D6ACHEALDH1A1MEN1KMT2A
SCHEMBL28667385 0.80 ALDH1A1 (0.42) TYRCYP2D6CYP1A2CYP2C19CYP3A4
SCHEMBL28667384 0.80 ALDH1A1 (0.42) TYRCYP2D6CYP1A2CYP2C19CYP3A4
SCHEMBL9243488 0.79 TYR (0.58) TYRALOX15MAPTGAAALDH1A1
SCHEMBL9081257 0.79 TYR (0.58) TYRCYP2D6CYP1A2CYP2C19CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 190 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10428216-B2 Golf ball incorporating a mixture of a thermoset and/or thermoplastic composition and a plurality of conductive nanoshelled structures ACUSHNET COMPANY (US) 2019-10-01 US disclosed
US-20190192922-A1 GOLF BALL COMPRISING MEDIUM HARDNESS GRADIENT CORE ACUSHNET COMPANY (US) 2019-06-27 US disclosed
US-10252115-B2 Golf ball incorporating positive hardness gradient thermoset polyurethane outer cover layer ACUSHNET COMPANY (US) 2019-04-09 US disclosed
US-10220263-B2 Golf balls comprising medium hardness gradient core ACUSHNET COMPANY (US) 2019-03-05 US disclosed
US-10130848-B2 Golf ball multilayer core having a gradient quotient ACUSHNET COMPANY (US) 2018-11-20 US disclosed
US-20180318654-A1 GOLF BALL INCORPORATING POSITIVE HARDNESS GRADIENT THERMOSET POLYURETHANE OUTER COVER LAYER ACUSHNET COMPANY (US) 2018-11-08 US disclosed
US-10112081-B2 Golf ball incorporating positive hardness gradient thermoset polyurethane outer cover layer ACUSHNET COMPANY (US) 2018-10-30 US disclosed
US-10035046-B2 Multilayer core golf ball having hardness gradient within and between each core layer ACUSHNET COMPANY (US) 2018-07-31 US disclosed
US-10029150-B2 Golf ball having medium positive gradient quotient and low trans content ACUSHNET COMPANY (US) 2018-07-24 US disclosed
US-10029151-B2 Multi-layer cover golf ball having a high acid casing layer ACUSHNET COMPANY (US) 2018-07-24 US disclosed
US-20090011863-A1 Negative Hardness Gradient Inner Core for Dual Core Golf Ball JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2009-01-08 US disclosed
US-20090008832-A1 Negative Hardness Gradient Core Produced from a Low, Temperature-Based Cure Cycle Index ACUSHNET COMPANY 2009-01-08 US disclosed
US-20090011855-A1 Golf Ball Core with Soft Outer Transition Volume and Negative Hardness Gradient ACUSHNET COMPANY 2009-01-08 US disclosed
US-7429221-B1 Negative hardness gradient outer core layer for dual core golf ball ACUSHNET COMPANY (US) 2008-09-30 US disclosed
US-7410429-B1 Negative hardness gradient inner core for dual core golf ball ACUSHNET COMPANY (US) 2008-08-12 US disclosed
US-20080153629-A1 Thick Outer Cover Layer Golf Ball ACUSHNET COMPANY 2008-06-26 US disclosed
US-20080146380-A1 Thick Outer Cover Layer Golf Ball ACUSHNET COMPANY 2008-06-19 US disclosed
US-20080146378-A1 Thick Inner Cover Multi-layer Golf Ball JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2008-06-19 US disclosed
US-3991139-A NORBORNENE DERIVATIVES, PHENOLS, ESTER THIOETHERS SHOWA DENKO KABUSHIKI KAISHA (JA) 1976-11-09 US disclosed
US-3984940-A Degradable plastic REICH MURRAY 1976-10-12 US disclosed