⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1758937 | 0.79 | TLR8 (0.41) | — | |
| SCHEMBL27637719 | 0.76 | TLR8 (0.41) | — | |
| SCHEMBL2095447 | 0.73 | — | — | |
| SCHEMBL24725806 | 0.73 | LMNA (0.32) | — | |
| SCHEMBL2095444 | 0.71 | — | — | |
| SCHEMBL16065691 | 0.71 | — | — | |
| SCHEMBL24345959 | 0.71 | — | — | |
| SCHEMBL657834 | 0.70 | JAK2 (0.31) | — | |
| SCHEMBL7091928 | 0.68 | — | — | |
| SCHEMBL22426584 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200255384-A9 | Compositions for the Treatment of Hypertension and/or Fibrosis | VECTUS BIOSYSTEMS LIMITED (AU) | 2020-08-13 | — | — | US | disclosed |