SCHEMBL2233261

SCHEMBL2233261

CCCCC(Oc1ccc(C(=O)O)cc1)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.54
TSHR P16473 1/20 0.54
PPARG P37231 6/20 0.53
PTGES O14684 1/20 0.53
ALOX5 P09917 1/20 0.53
KMT2A Q03164 1/20 0.53
PLA2G4B P0C869 3/20 0.53
PPARA Q07869 5/20 0.52
FOLH1 Q04609 1/20 0.52
RARB P10826 4/20 0.50
CTRC Q99895 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11589038 0.95 TP53 (0.56) TP53TSHRPPARGPTGESALOX5
SCHEMBL8133487 0.94 TP53 (0.59) TP53TSHRPPARGKMT2APLA2G4B
SCHEMBL28349098 0.94 TP53 (0.59) TP53TSHRPPARGKMT2APLA2G4B
SCHEMBL2255421 0.94 TP53 (0.59) TP53TSHRPPARGKMT2APLA2G4B
SCHEMBL2230124 0.90 PPARG (0.63) TP53TSHRPPARGKMT2APLA2G4B
SCHEMBL1564807 0.86 PPARA (0.59) PPARGPTGESALOX5PPARACTRC
SCHEMBL31144647 0.85 CTRC (0.63) TP53TSHRPPARGPTGESALOX5
SCHEMBL8935884 0.85 PPARG (0.64) PPARGPTGESALOX5PPARAFOLH1
SCHEMBL289442 0.85 PPARG (0.64) PPARGPTGESALOX5PPARAFOLH1
SCHEMBL1565681 0.84 PPARA (0.57) PPARGPTGESALOX5PPARACTRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012036737-A3 RECEIVER FILL VALVE AND CONTROL METHOD TRANE INTERNATIONAL INC. (US) 2012-05-10 WO disclosed
EP-1466724-B1 Thermoplastic resin composition and multi-layer laminate MITSUBISHI CHEM CORP (JP) 2011-12-07 EP disclosed
US-7977432-B2 Comprising at least two polymer end blocks and at least one saturated polymer interior block wherein each end block is resistant to lithiation and at least one interior block is susceptible to lithiation; for semi-permeable membrane with high water transport properties that maintains wet strength KRATON POLYMERS U.S. LLC (US) 2011-07-12 US disclosed
US-20080171828-A1 FUNCTIONALIZED BLOCK COPOLYMERS, METHOD FOR MAKING SAME, AND VARIOUS USES FOR SUCH BLOCK COPOLYMERS KRATON POLYMERS U.S. LLC. (US) 2008-07-17 US disclosed
EP-1618157-B1 USE OF POLYANHYDRIDES IN ANTIFOULING PAINT AND ANTIFOULING PAINT CONTAINING POLYANHYDRIDES JOTUN AS (NO) 2007-03-14 EP disclosed
EP-0918812-B1 WETTABLE POLYMER FIBERS TECHMER PM (US) 2004-12-01 EP disclosed
US-6815080-B2 GAS-BARRIER PROPERTY, IMPACT STRENGTH, FLUIDITY UPON MELTING AND, THEREFORE, A GOOD INJECTION MOLDABILITY MITSUBISHI CHEMICAL CORPORATION (JP) 2004-11-09 US disclosed
EP-1466724-A2 Thermoplastic resin composition and multi-layer laminate Mitsubishi Chemical Corporation (JP) 2004-10-13 EP disclosed
US-20040006182-A1 Thermoplastic resin composition and multi-layer laminate MITSUBISHI CHEMICAL CORPORATION (JP) 2004-01-08 US disclosed
US-6586091-B2 Adhesive strength which comprises an adhesive polymer composition layer and a gas-barrier resin layer comprising a polyamide resin or an ethylene-vinyl alcohol copolymer, the adhesive polymer composition layer comprising a modified MITSUBISHI CHEMICAL CORPORATION (JP) 2003-07-01 US disclosed
US-4102854-A Multicomponent polyolefin-block copolymer polycarbonate blends SHELL OIL COMPANY (US) 1978-07-25 US disclosed
US-4101605-A HYDROGENATED CONJUGATED DIENE-MONOALKENYL ARENE COPOLYMER SHELL OIL COMPANY (US) 1978-07-18 US disclosed
US-4090996-A IMPACT STRENGTH SHELL OIL COMPANY (US) 1978-05-23 US disclosed
US-4088627-A Multicomponent polyurethane-block copolymer blends SHELL OIL COMPANY (US) 1978-05-09 US disclosed
US-4088626-A Multicomponent polysulfone-block copolymer-polymer blends SHELL OIL COMPANY (US) 1978-05-09 US disclosed
US-4085163-A HYDROGENATED MONOALKENYL ARYL-DIENE BLOCK COPOLYMER SHELL OIL COMPANY (US) 1978-04-18 US disclosed
US-4081424-A OLEFIN COPOLYMERS/AROMATIC/, COPOLYENES/CONJUGATED/, THERMOPLASTIC RESIN SHELL OIL COMPANY (US) 1978-03-28 US disclosed
US-4080357-A Multicomponent halogenated thermoplastic-block copolymer-polymer blends SHELL OIL COMPANY (US) 1978-03-21 US disclosed
US-4080356-A Multicomponent polyacetal-block copolymer-polymer blends SHELL OIL COMPANY (US) 1978-03-21 US disclosed
US-4079046-A Multiple polyesterification process MONSANTO COMPANY, ST. LOUIS, MISSOURI (US) 1978-03-14 US disclosed