SCHEMBL2233264

SCHEMBL2233264

O=C(O)CCCCCOc1ccc(C(=O)O)cc1

nearest known ligand 0.71

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 2/20 0.71
TP53 P04637 1/20 0.70
TSHR P16473 1/20 0.70
PLA2G4B P0C869 5/20 0.68
RARB P10826 3/20 0.64
HTT P42858 3/20 0.64
PKM P14618 1/20 0.62
PLA2G4A P47712 1/20 0.60
POLB P06746 1/20 0.59
APEX1 P27695 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
ALDH1A1 P00352 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
GAA P10253 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11589042 1.00 PPARA (0.71) PPARATP53TSHRPLA2G4BRARB
SCHEMBL8133488 1.00 PPARA (0.71) PPARATP53TSHRPLA2G4BRARB
SCHEMBL28279260 1.00 PPARA (0.71) PPARATP53TSHRPLA2G4BRARB
SCHEMBL2255415 1.00 PPARA (0.71) PPARATP53TSHRPLA2G4BRARB
SCHEMBL2230125 0.98 PPARA (0.73) PPARATP53TSHRPLA2G4BRARB
Sebacic Acid SCHEMBL5050874 0.96 PLA2G4B (0.68) PPARATP53TSHRPLA2G4BRARB
SCHEMBL2231223 0.93 PKM (0.67) PPARATP53TSHRPLA2G4BRARB
Sebacic Acid SCHEMBL28178734 0.92 TP53 (0.85) PPARATP53TSHRPLA2G4BRARB
SCHEMBL2180731 0.91 TP53 (0.82) TP53TSHRPLA2G4BRARBHTT
SCHEMBL2181009 0.91 TP53 (0.82) TP53TSHRPLA2G4BRARBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0343889-A2 Novel polyanhydrides HOECHST CELANESE CORPORATION (US) 1989-11-29 EP claimed
US-4868274-A Polyanhydride from carboxy aryloxy alkanoic acid HOECHST CELANESE CORP. (US) 1989-09-19 US claimed
US-8344175-B2 Liquid crystal compositions, polymer networks derived therefrom and process for making the same E I DU PONT DE NEMOURS AND COMPANY (US) 2013-01-01 US disclosed
US-8344175-B2 Liquid crystal compositions, polymer networks derived therefrom and process for making the same E I DU PONT DE NEMOURS AND COMPANY (US) 2013-01-01 US disclosed
US-8334393-B2 Chiral compounds and liquid crystal compositions and polymer networks derived therefrom E I DU PONT DE NEMOURS AND COMPANY (US) 2012-12-18 US disclosed
US-8334393-B2 Chiral compounds and liquid crystal compositions and polymer networks derived therefrom E I DU PONT DE NEMOURS AND COMPANY (US) 2012-12-18 US disclosed
WO-2012036737-A3 RECEIVER FILL VALVE AND CONTROL METHOD TRANE INTERNATIONAL INC. (US) 2012-05-10 WO disclosed
EP-1466724-B1 Thermoplastic resin composition and multi-layer laminate MITSUBISHI CHEM CORP (JP) 2011-12-07 EP disclosed
US-7977432-B2 Comprising at least two polymer end blocks and at least one saturated polymer interior block wherein each end block is resistant to lithiation and at least one interior block is susceptible to lithiation; for semi-permeable membrane with high water transport properties that maintains wet strength KRATON POLYMERS U.S. LLC (US) 2011-07-12 US disclosed
US-20110163267-A1 CHIRAL COMPOUNDS AND LIQUID CRYSTAL COMPOSITIONS AND POLYMER NETWORKS DERIVED THEREFROM E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-07-07 US disclosed
US-20110163267-A1 CHIRAL COMPOUNDS AND LIQUID CRYSTAL COMPOSITIONS AND POLYMER NETWORKS DERIVED THEREFROM E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-07-07 US disclosed
US-4101605-A HYDROGENATED CONJUGATED DIENE-MONOALKENYL ARENE COPOLYMER SHELL OIL COMPANY (US) 1978-07-18 US disclosed
US-4090996-A IMPACT STRENGTH SHELL OIL COMPANY (US) 1978-05-23 US disclosed
US-4088627-A Multicomponent polyurethane-block copolymer blends SHELL OIL COMPANY (US) 1978-05-09 US disclosed
US-4088626-A Multicomponent polysulfone-block copolymer-polymer blends SHELL OIL COMPANY (US) 1978-05-09 US disclosed
US-4085163-A HYDROGENATED MONOALKENYL ARYL-DIENE BLOCK COPOLYMER SHELL OIL COMPANY (US) 1978-04-18 US disclosed
US-4081424-A OLEFIN COPOLYMERS/AROMATIC/, COPOLYENES/CONJUGATED/, THERMOPLASTIC RESIN SHELL OIL COMPANY (US) 1978-03-28 US disclosed
US-4080357-A Multicomponent halogenated thermoplastic-block copolymer-polymer blends SHELL OIL COMPANY (US) 1978-03-21 US disclosed
US-4080356-A Multicomponent polyacetal-block copolymer-polymer blends SHELL OIL COMPANY (US) 1978-03-21 US disclosed
US-4079046-A Multiple polyesterification process MONSANTO COMPANY, ST. LOUIS, MISSOURI (US) 1978-03-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110163267-A1 CHIRAL COMPOUNDS AND LIQUID CRYSTAL COMPOSITIONS AND POLYMER NETWORKS DERIVED THEREFROM CCNB1, F2, CYP4F11 PPARA 3889/4885TP53 2101/4885TSHR 3498/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.