Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16224920 | 1.00 | SMN1; SMN2 (0.51) | SMN1; SMN2MEN1KMT2ACHRM2HRH4 | |
| SCHEMBL24067917 | 0.94 | MEN1 (0.43) | SMN1; SMN2MEN1KMT2ACHRM2HRH4 | |
| SCHEMBL21171674 | 0.87 | SLC6A4 (0.47) | SMN1; SMN2MEN1KMT2AACHESCN8A | |
| SCHEMBL9156094 | 0.86 | ACHE (0.56) | SMN1; SMN2MEN1KMT2ACHRM2HRH4 | |
| SCHEMBL4630662 | 0.86 | ACHE (0.56) | SMN1; SMN2MEN1KMT2ACHRM2HRH4 | |
| Hydrochloric Acid SCHEMBL3964021 | 0.84 | ACHE (0.55) | SMN1; SMN2MEN1KMT2ACHRM2HRH4 | |
| Hydrochloric Acid SCHEMBL3963988 | 0.84 | ACHE (0.55) | SMN1; SMN2MEN1KMT2ACHRM2HRH4 | |
| Hydrochloric Acid SCHEMBL3963138 | 0.84 | ACHE (0.55) | SMN1; SMN2MEN1KMT2ACHRM2HRH4 | |
| SCHEMBL20313356 | 0.84 | CA12 (0.51) | SMN1; SMN2MEN1KMT2ACHRM2HRH4 | |
| SCHEMBL20831858 | 0.83 | SLC6A4 (0.44) | CHRM2ACHESCN8A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3062783-B1 | IMAGING HISTONE DEACETYLASES WITH A RADIOTRACER USING POSITRON EMISSION TOMOGRAPHY | MASSACHUSETTS GEN HOSPITAL (US) | 2020-08-12 | — | — | EP | disclosed |