SCHEMBL223333

SCHEMBL223333

CCCCC[C@H]1CC[C@H](c2ccc(-c3ccc(C#N)cc3)cc2)CC1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.49
HSD17B10 Q99714 1/20 0.49
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
MAPK1 P28482 1/20 0.43
HRH3 Q9Y5N1 4/20 0.42
KCNH2 Q12809 1/20 0.42
CYP2C9 P11712 1/20 0.42
HRH2 P25021 2/20 0.40
HRH1 P35367 2/20 0.40
MAPT P10636 2/20 0.40
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40
GRM2 Q14416 1/20 0.40
GRIA1 P42261 1/20 0.40
GRIA2 P42262 1/20 0.40
GRIA3 P42263 1/20 0.40
SPHK1 Q9NYA1 2/20 0.40
GAA P10253 1/20 0.39
KIF11 P52732 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL223334 1.00 TSHR (0.49) TSHRHSD17B10MEN1KMT2AMAPK1
SCHEMBL11524189 0.99 TSHR (0.51) TSHRHSD17B10MEN1KMT2AMAPK1
SCHEMBL11523768 0.99 TSHR (0.51) TSHRHSD17B10MEN1KMT2AMAPK1
SCHEMBL11523764 0.99 TSHR (0.51) TSHRHSD17B10MEN1KMT2AMAPK1
SCHEMBL11525037 0.99 TSHR (0.51) TSHRHSD17B10MEN1KMT2AMAPK1
SCHEMBL11524002 0.99 TSHR (0.51) TSHRHSD17B10MEN1KMT2AMAPK1
SCHEMBL11524192 0.99 TSHR (0.51) TSHRHSD17B10MEN1KMT2AMAPK1
SCHEMBL11524006 0.99 TSHR (0.51) TSHRHSD17B10MEN1KMT2AMAPK1
SCHEMBL9632203 0.99 TSHR (0.51) TSHRHSD17B10MEN1KMT2AMAPK1
SCHEMBL11527385 0.99 TSHR (0.51) TSHRHSD17B10MEN1KMT2AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 376 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116731707-A TTA-UC system enhanced up-conversion luminescence method doped with chiral nematic liquid crystal 苏州科技大学 2023-09-12 CN claimed
CN-116206540-A Multi-mode display layer made of up-conversion liquid crystal microcapsules and display application 苏州科技大学 2023-06-02 CN claimed
CN-113777061-B Acetone gas fiber sensor visible to naked eyes and preparation method thereof 江南大学 2023-01-31 CN claimed
CN-113862823-B Bamboo joint-like liquid crystal fiber and preparation method thereof 江南大学 2022-08-09 CN claimed
US-RE37270-E1 EXCELLENT ELECTRO-OPTIC STEEPNESS AND VIEWING ANGLE COMBINED WITH BIREFRINGENCE FOR USE IN STANDARD DISPLAY CELLS; MIXTURE OF 4-CYANO-3-FLUOROPHENYL BENZOATES, BENZONITRILES, ALKYLPHENYL ESTERS OF CYCLOHEXANE OR PHENYLCARBOXYLIC ACIDS MERCK PATENT GESELLSCHAFT (DE) 2001-07-10 US claimed
EP-0285617-B1 LIQUID CRYSTAL PHASE MERCK PATENT GmbH (DE) 1991-12-27 EP claimed
US-4886621-A ACCEPTABLE COMBINATION OF THRESHOLD STEEPNESS, VIEWING ANGLE AND TEMPERATURE DEPENDENCE AT LOW THRESHOLD VOLTAGE MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1989-12-12 US claimed
US-4583826-A Phenylethanes HOFFMANN-LA ROCHE INC. (US) 1986-04-22 US claimed
US-4154697-A Liquid crystalline hexahydroterphenyl derivatives MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) 1979-05-15 US claimed
JP-57025381-A None JP disclosed
JP-57018778-A None JP disclosed
CN-119040007-B Cholesteric liquid crystal microcapsule and preparation method thereof 上海纳琳威科技股份有限公司 2025-03-07 CN disclosed
US-20250011590-A1 OPTICAL FILM AND POLARIZING PLATE TOSOH CORPORATION (JP) 2025-01-09 US disclosed
CN-119040007-A Cholesteric liquid crystal microcapsule and preparation method thereof 上海纳琳威科技股份有限公司 2024-11-29 CN disclosed
EP-0014840-B1 FLUORPHENYL-TRANS-CYCLOHEXANES, PROCESS FOR THEIR PREPARATION, LIQUID CRYSTALLINE DIELECTRICS CONTAINING THEM AND ELECTROOPTICAL DISPLAYING MEANS MERCK PATENT GmbH (DE) 1982-01-06 EP disclosed
US-4302352-A Fluorophenylcyclohexanes, the preparation thereof and their use as components of liquid crystal dielectrics MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1981-11-24 US disclosed
EP-0031021-A1 Tetrahydroquinazolines, process for their preparation, liquid crystalline dielectrics containing them and electro-optical display element MERCK PATENT GmbH (DE) 1981-07-01 EP disclosed
EP-0030277-A1 Partially hydrogenated oligo-1,4-phenylenes, dielectrics containing them and electro-optical indicating device MERCK PATENT GmbH (DE) 1981-06-17 EP disclosed
EP-0014840-A1 Fluorphenyl-trans-cyclohexanes, process for their preparation, liquid crystalline dielectrics containing them and electrooptical displaying means MERCK PATENT GmbH (DE) 1980-09-03 EP disclosed
US-4154697-A Liquid crystalline hexahydroterphenyl derivatives MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) 1979-05-15 US disclosed