Biphenyl

Biphenyl

SCHEMBL2233389

CCCCCCCCCCOCCCCCCCCCC.[NaH].[NaH].c1ccc(-c2ccccc2)cc1

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.48
SOAT1 P35610 1/20 0.47
MEN1 O00255 1/20 0.47
THRB P10828 1/20 0.47
HTT P42858 1/20 0.47
KMT2A Q03164 1/20 0.47
MAPT P10636 1/20 0.47
PTPN1 P18031 1/20 0.46
TSHR P16473 3/20 0.46
ALDH1A1 P00352 3/20 0.46
LMNA P02545 1/20 0.46
RARB P10826 4/20 0.45
TP53 P04637 1/20 0.43
CYP3A4 P08684 1/20 0.43
MAPK1 P28482 1/20 0.43
CNR2 P34972 1/20 0.43
HPGD P15428 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL7727587 1.00 LTA4H (0.48) LTA4HSOAT1MEN1THRBHTT
Biphenyl SCHEMBL941924 1.00 LTA4H (0.48) LTA4HSOAT1MEN1THRBHTT
Biphenyl SCHEMBL3981158 1.00 LTA4H (0.48) LTA4HSOAT1MEN1THRBHTT
Biphenyl SCHEMBL18141067 1.00 LTA4H (0.48) LTA4HSOAT1MEN1THRBHTT
Biphenyl SCHEMBL19307249 1.00 LTA4H (0.48) LTA4HSOAT1MEN1THRBHTT
Biphenyl SCHEMBL18140727 1.00 LTA4H (0.48) LTA4HSOAT1MEN1THRBHTT
Biphenyl SCHEMBL18140448 1.00 LTA4H (0.48) LTA4HSOAT1MEN1THRBHTT
Biphenyl SCHEMBL18139419 1.00 LTA4H (0.48) LTA4HSOAT1MEN1THRBHTT
Biphenyl SCHEMBL18139229 1.00 LTA4H (0.48) LTA4HSOAT1MEN1THRBHTT
Biphenyl SCHEMBL18140000 1.00 LTA4H (0.48) LTA4HSOAT1MEN1THRBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4223286-A2 SPRAY DRIED COMPOSITIONS HAVING DIFFERENT DISSOLUTION PROFILES AND PROCESSES FOR THEIR PREPARATION SpecGx LLC (US) 2023-08-09 EP disclosed
EP-3154528-B1 SPRAY DRIED COMPOSITIONS HAVING DIFFERENT DISSOLUTION PROFILES AND PROCESSES FOR THEIR PREPARATION SpecGx LLC (US) 2023-04-05 EP disclosed
EP-3702361-B1 MICRO RNA ISOLATION FROM BIOLOGICAL FLUID SIGMA ALDRICH CO LLC (US) 2022-08-31 EP disclosed
EP-3702361-A1 MICRO RNA ISOLATION FROM BIOLOGICAL FLUID Sigma Aldrich Co. LLC (US) 2020-09-02 EP disclosed
US-10711266-B2 Micro RNA isolation from a biological sample SIGMA-ALDRICH CO. LLC (US) 2020-07-14 US disclosed
US-20190144850-A1 MICRO RNA ISOLATION FROM BIOLOGICAL FLUID SIGMA-ALDRICH CO. LLC (US) 2019-05-16 US disclosed
US-10131902-B2 Micro RNA isolation from biological fluid SIGMA-ALDRICH CO. LLC (US) 2018-11-20 US disclosed
EP-3154528-A1 SPRAY DRIED COMPOSITIONS HAVING DIFFERENT DISSOLUTION PROFILES AND PROCESSES FOR THEIR PREPARATION Mallinckrodt LLC (US) 2017-04-19 EP disclosed
US-20160376582-A1 MICRO RNA ISOLATION FROM BIOLOGICAL FLUID SIGMA-ALDRICH CO. LLC (US) 2016-12-29 US disclosed
EP-3074413-A1 MICRO RNA ISOLATION FROM BIOLOGICAL FLUID Sigma-Aldrich Co. LLC (US) 2016-10-05 EP disclosed
WO-2015191282-A1 SPRAY DRIED COMPOSITIONS HAVING DIFFERENT DISSOLUTION PROFILES AND PROCESSES FOR THEIR PREPARATION MALLINCKRODT LLC (US) 2015-12-17 WO disclosed
WO-2015094609-A1 MICRO RNA ISOLATION FROM BIOLOGICAL FLUID SIGMA-ALDRICH CO. LLC (US) 2015-06-25 WO disclosed
EP-2115131-B1 STABILIZED COMPOSITIONS OF THERMOSTABLE DNA POLYMERASE AND ANIONIC DETERGENT SIGMA ALDRICH CO LLC (US) 2013-07-31 EP disclosed
US-8404464-B2 Methods of using stabilized compositions of thermostable DNA polymerase and anionic detergent SIGMA-ALDRICH CO., LLC (US) 2013-03-26 US disclosed
US-20110312035-A1 STABILIZED COMPOSITIONS OF THERMOSTABLE DNA POLYMERASE AND ANIONIC OR ZWITTERIONIC DETERGENT SIGMA-ALDRICH CO. (US) 2011-12-22 US disclosed
US-7972828-B2 a mixture of polymerases and anionic or zwitterionic surfactants, used for protecting DNA during genetic replication SIGMA-ALDRICH CO. (US) 2011-07-05 US disclosed
WO-2010083844-A1 METHODS AND USES FOR RNA EXTRACT AND STORAGE QUANTIBACT A/S (DK) 2010-07-29 WO disclosed
EP-2115131-A2 STABILIZED COMPOSITIONS OF THERMOSTABLE DNA POLYMERASE AND ANIONIC OR ZWITTERIONIC DETERGENT Sigma-Aldrich Co. (US) 2009-11-11 EP disclosed
WO-2008077017-A2 STABILIZED COMPOSITIONS OF THERMOSTABLE DNA POLYMERASE AND ANIONIC OR ZWITTERIONIC DETERGENT SIGMA-ALDRICH CO. (US) 2008-06-26 WO disclosed
US-20080145910-A1 STABILIZED COMPOSITIONS OF THERMOSTABLE DNA POLYMERASE AND ANIONIC OR ZWITTERIONIC DETERGENT SIGMA ALDRICH COMPANY (US) 2008-06-19 US disclosed