Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12614293 | 0.76 | CYP2D6 (0.31) | CYP2D6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL12614287 | 0.76 | CYP2D6 (0.31) | CYP2D6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL7562972 | 0.75 | CYP2D6 (0.41) | CYP2D6CA1CA2CA7HDAC3 | |
| SCHEMBL4333800 | 0.73 | CYP2D6 (0.35) | CYP2D6CA1CA2CA7 | |
| SCHEMBL27420033 | 0.71 | NR1D1 (0.38) | CYP2D6CA1CA2CA7HDAC3 | |
| SCHEMBL22966171 | 0.70 | TDP1 (0.37) | — | |
| SCHEMBL4331172 | 0.70 | — | — | |
| SCHEMBL12614291 | 0.70 | CYP2D6 (0.39) | CYP2D6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL7563852 | 0.69 | CYP2D6 (0.34) | CYP2D6CA1CA2CA7HDAC3 | |
| SCHEMBL4338603 | 0.69 | CYP2D6 (0.34) | CYP2D6CA1CA2CA7HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11639929-B2 | Universal histidine-tag binding compounds and methods of use thereof as fluorescent probes and sensors | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2023-05-02 | — | — | US | disclosed |
| US-11639929-B2 | Universal histidine-tag binding compounds and methods of use thereof as fluorescent probes and sensors | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2023-05-02 | — | — | US | disclosed |
| US-20210156867-A1 | QUINOLINE BASED CYANINE DYE TURN-ON FLUORESCENT PROBES AND METHODS OF USE THEREOF | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2021-05-27 | — | — | US | disclosed |
| US-20200256857-A1 | UNIVERSAL HISTIDINE-TAG BINDING COMPOUNDS AND METHODS OF USE THEREOF AS FLUORESCENT PROBES AND SENSORS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2020-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11639929-B2 | Universal histidine-tag binding compounds and methods of use thereof as fluorescent probes and sensors | HCLS1, PHF6, PHPT1 | CYP2D6 4632/4885CA1 2275/4885CA2 3017/4885 |
| US-20200256857-A1 | UNIVERSAL HISTIDINE-TAG BINDING COMPOUNDS AND METHODS OF USE THEREOF AS FLUORESCENT PROBES AND SENSORS | HCLS1, PHF6, PHPT1 | CYP2D6 4632/4885CA1 2275/4885CA2 3017/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.