Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.47 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.47 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.47 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL9995855 | 0.96 | CA4 (0.44) | CA4GLRA1SLC6A9OR51E2CASP1 | |
| Glycine SCHEMBL10906749 | 0.96 | CA4 (0.44) | CA4GLRA1SLC6A9OR51E2CASP1 | |
| Glycine SCHEMBL2161269 | 0.96 | CA4 (0.44) | CA4GLRA1SLC6A9OR51E2CASP1 | |
| Glycine SCHEMBL3121145 | 0.96 | CA4 (0.44) | CA4GLRA1SLC6A9OR51E2CASP1 | |
| Glycine SCHEMBL4728488 | 0.96 | CA4 (0.44) | CA4GLRA1SLC6A9OR51E2CASP1 | |
| Glycine SCHEMBL5187484 | 0.96 | CA4 (0.44) | CA4GLRA1SLC6A9OR51E2CASP1 | |
| Glycine SCHEMBL4661565 | 0.96 | — | — | |
| Glycine SCHEMBL5943682 | 0.96 | CA4 (0.44) | CA4GLRA1SLC6A9OR51E2CASP1 | |
| Glycine SCHEMBL5689090 | 0.96 | CA4 (0.44) | CA4GLRA1SLC6A9OR51E2CASP1 | |
| Glycine SCHEMBL142870 | 0.96 | CA4 (0.44) | CA4GLRA1SLC6A9OR51E2CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2836 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122075451-A | Tilapia paste composition, paste and preparation method thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-118436621-B | Capsaicin electrode slice | NANJING DING SHI MEDICAL DEVICES Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-122075605-A | Preparation method and application of gel emplastrum | — | 2026-05-26 | — | — | CN | claimed |
| CN-122005698-A | Temperature control type dragon's blood cataplasm and preparation method and application thereof | 江油市九〇三医院 | 2026-05-12 | — | — | CN | claimed |
| CN-121570441-A | Timolol maleate gel emplastrum and preparation method thereof | 云南白药集团无锡药业有限公司 | 2026-02-27 | — | — | CN | claimed |
| CN-120078746-A | Blood circulation activating and vein relaxing hydrogel patch and preparation method thereof | 吉林省中医药科学院（吉林省中医药科学院第一临床医院） | 2025-06-03 | — | — | CN | claimed |
| CN-120078750-A | Anti-inflammatory pain-relieving cataplasm for improving drug stability and preparation method thereof | 湖南九典制药股份有限公司 | 2025-06-03 | — | — | CN | claimed |
| CN-120024097-A | Organic microcapsule temperature-control gel layer, hydrogel temperature-reduction patch and preparation methods thereof | 武汉晶岚医疗器械有限公司 | 2025-05-23 | — | — | CN | claimed |
| CN-119970859-A | Traditional Chinese medicine composition for treating recurrent oral ulcer, emplastrum and preparation method | 韩瑞阳 | 2025-05-13 | — | — | CN | claimed |
| CN-118304244-B | Dual gel sebum membrane and preparation method thereof | 佛山拜澳生物科技有限公司 | 2025-05-13 | — | — | CN | claimed |
| WO-1994002140-A1 | PHARMACEUTICAL COMPOSITION CONTAINING ANTIULCER AGENT | ASTRA AKTIEBOLAG (SE) | 1994-02-03 | — | — | WO | claimed |
| EP-0578768-A1 | INGESTIBLE PHARMACEUTICAL COMPOSITIONS FOR TREATING UPPER GASTROINTESTINAL TRACT DISTRESS. | PROCTER & GAMBLE (US) | 1994-01-19 | — | — | EP | claimed |
| US-5250569-A | Amino acid flavorings of aluminum astringent for oral use | GODFREY SCIENCE & DESIGN, INC. (US) | 1993-10-05 | — | — | US | claimed |
| EP-0423139-B1 | A METHOD OF PRODUCING A ZEOLITE BETA HYDROCARBON CONVERSION CATALYST | MOBIL OIL CORPORATION (US) | 1993-03-17 | — | — | EP | claimed |
| US-5162378-A | Cetyl dimethicone copolyol, water, silicone, and alcohol; moisturizer, antiperspirant | REVLON CONSUMER PRODUCTS CORPORATION (US) | 1992-11-10 | — | — | US | claimed |
| WO-1992017164-A1 | INGESTIBLE PHARMACEUTICAL COMPOSITIONS FOR TREATING UPPER GASTROINTESTINAL TRACT DISTRESS | THE PROCTER & GAMBLE COMPANY (US) | 1992-10-15 | — | — | WO | claimed |
| EP-0350701-A2 | Pharmaceutical cmpositions for oral administration having analgesic and anti-inflammatory activity, possessing excellent palatability and being free of irritating effects on mucous membranes | FARMA RESA S.r.l. (IT) | 1990-01-17 | — | — | EP | claimed |
| EP-0295071-A2 | Low residue wax emulsion antiperspirant sticks | THE PROCTER & GAMBLE COMPANY (US) | 1988-12-14 | — | — | EP | claimed |
| US-4716153-A | STABILIZER AND DISSOLUTION PROMOTER | TOYO JOZO COMPANY, LTD. (JP) | 1987-12-29 | — | — | US | claimed |
| EP-0094116-A2 | Therapeutic granules | THE PROCTER & GAMBLE COMPANY (US) | 1983-11-16 | — | — | EP | claimed |