Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | BCL9 | O00512 | 1/20 | 0.45 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22334757 | 0.83 | KMT2A (0.51) | KMT2ASMN1; SMN2BCL9CTNNB1NPC1 | |
| SCHEMBL27652865 | 0.82 | KMT2A (0.55) | KMT2ASMN1; SMN2BCL9CTNNB1NPC1 | |
| SCHEMBL31094048 | 0.80 | KMT2A (0.57) | KMT2ASMN1; SMN2BCL9CTNNB1NPC1 | |
| SCHEMBL32684888 | 0.80 | KMT2A (0.57) | KMT2ASMN1; SMN2BCL9CTNNB1NPC1 | |
| SCHEMBL32685014 | 0.80 | KMT2A (0.57) | KMT2ASMN1; SMN2BCL9CTNNB1NPC1 | |
| SCHEMBL9016841 | 0.80 | KMT2A (0.57) | KMT2ASMN1; SMN2BCL9CTNNB1NPC1 | |
| SCHEMBL15987811 | 0.80 | KMT2A (0.57) | KMT2ASMN1; SMN2BCL9CTNNB1NPC1 | |
| SCHEMBL10407329 | 0.80 | KMT2A (0.65) | KMT2ASMN1; SMN2BCL9CTNNB1NPC1 | |
| SCHEMBL22334843 | 0.79 | KMT2A (0.47) | KMT2ASMN1; SMN2BCL9CTNNB1NPC1 | |
| SCHEMBL11526720 | 0.79 | KMT2A (0.56) | KMT2ASMN1; SMN2BCL9CTNNB1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4039220-B1 | DENTAL MATERIALS ON THE BASIS OF POLYMERISABLE THIOUREA DERIVATIVES | IVOCLAR VIVADENT AG (LI) | 2022-12-28 | — | — | EP | disclosed |
| EP-3692976-A1 | DENTAL MATERIALS BASED ON REDOX SYSTEMS WITH LOW ODOR CUMOLHYDE-HYDROPEROXIDE DERIVATIVES | Ivoclar Vivadent AG (LI) | 2020-08-12 | — | — | EP | disclosed |