Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 10/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 4/20 | 0.41 |
| ▸ | HTR2B | P41595 | 6/20 | 0.38 |
| ▸ | HTR2A | P28223 | 4/20 | 0.38 |
| ▸ | MAOB | P27338 | 4/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL5834701 | 0.78 | HTR2C (0.55) | HTR2CKDM1AHTR2BHTR2AMAOB | |
| SCHEMBL22334952 | 0.77 | ALDH1A1 (0.57) | HTR2CALDH1A1KDM1AMAOBMAOA | |
| SCHEMBL20308867 | 0.76 | KDM1A (0.48) | KDM1AMAOBMAOA | |
| SCHEMBL22334943 | 0.76 | ALDH1A1 (0.38) | HTR2CALDH1A1HTR2BHTR2AMAOB | |
| SCHEMBL22335047 | 0.76 | HTR2C (0.54) | HTR2CKDM1AHTR2BHTR2AMAOB | |
| SCHEMBL22334901 | 0.74 | KDM1A (0.65) | KDM1AMAOBMAOARCOR1 | |
| SCHEMBL22335090 | 0.73 | HTT (0.53) | KDM1AMAOBMAOARCOR1 | |
| SCHEMBL28829908 | 0.72 | HTR2C (0.56) | HTR2CKDM1AMAOBMAOA | |
| SCHEMBL20308864 | 0.69 | KDM1A (0.44) | KDM1AMAOBMAOARCOR1 | |
| SCHEMBL14855299 | 0.68 | ALDH1A1 (0.64) | ALDH1A1SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2928457-B1 | CYCLOPROPYLAMINE DERIVATIVES USEFUL AS INHIBITORS OF HISTONE DEMETHYLASES KDM1A | ST EUROPEO DI ONCOLOGIA S R L (IT) | 2020-08-12 | — | — | EP | disclosed |