Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.33 |
| ▸ | BMP1 | P13497 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
| ▸ | TGM2 | P21980 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2238348 | 0.86 | LMNA (0.39) | ACE | |
| SCHEMBL2233577 | 0.85 | ACE (0.34) | ACEDPP8DPP7FOLH1MAPT | |
| SCHEMBL2237273 | 0.83 | ACE (0.36) | ACEDPP8DPP7FOLH1MAPT | |
| SCHEMBL2236787 | 0.82 | MEN1 (0.47) | ACE | |
| SCHEMBL2238532 | 0.82 | MEN1 (0.47) | ACE | |
| SCHEMBL2234466 | 0.82 | MEN1 (0.47) | ACE | |
| SCHEMBL2236552 | 0.82 | ACE (0.35) | ACEDPP8DPP7FOLH1MAPT | |
| SCHEMBL2236260 | 0.82 | ACE (0.34) | ACEDPP8DPP7 | |
| SCHEMBL2233508 | 0.82 | ACE (0.35) | ACEDPP8DPP7FOLH1MAPT | |
| SCHEMBL2381593 | 0.82 | ACE (0.35) | ACEDPP8DPP7FOLH1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2361910-A1 | COMPOUND HAVING TAFIA INHIBITORY ACTIVITY | Taisho Pharmaceutical Co., Ltd. (JP) | 2011-08-31 | — | — | EP | disclosed |