SCHEMBL2233593

SCHEMBL2233593

N=C(N)NC1CCCCC1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 5/20 0.50
SMN1; SMN2 Q16637 4/20 0.50
SIGMAR1 Q99720 4/20 0.50
NPC1 O15118 3/20 0.50
RAB9A P51151 3/20 0.50
ALDH1A1 P00352 2/20 0.50
CYP3A4 P08684 2/20 0.50
TP53 P04637 1/20 0.50
MAPT P10636 1/20 0.50
KDM4E B2RXH2 1/20 0.50
EPHX2 P34913 1/20 0.50
LMNA P02545 1/20 0.48
GAA P10253 1/20 0.48
NOS2 P35228 1/20 0.42
MMP2 P08253 2/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
MMP8 P22894 1/20 0.41
CA9 Q16790 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14780962 1.00 EPHX1 (0.50) EPHX1SMN1; SMN2SIGMAR1NPC1RAB9A
SCHEMBL14447237 1.00 EPHX1 (0.50) EPHX1SMN1; SMN2SIGMAR1NPC1RAB9A
SCHEMBL14447399 1.00 EPHX1 (0.50) EPHX1SMN1; SMN2SIGMAR1NPC1RAB9A
SCHEMBL19359634 1.00 EPHX1 (0.50) EPHX1SMN1; SMN2SIGMAR1NPC1RAB9A
SCHEMBL13030308 1.00 EPHX1 (0.50) EPHX1SMN1; SMN2SIGMAR1NPC1RAB9A
SCHEMBL23736061 1.00 EPHX1 (0.50) EPHX1SMN1; SMN2SIGMAR1NPC1RAB9A
SCHEMBL19359635 1.00 EPHX1 (0.50) EPHX1SMN1; SMN2SIGMAR1NPC1RAB9A
Hydrochloric Acid SCHEMBL23736062 0.97 SIGMAR1 (0.48) EPHX1SMN1; SMN2SIGMAR1NPC1RAB9A
Hydrochloric Acid SCHEMBL16702587 0.97 SIGMAR1 (0.48) EPHX1SMN1; SMN2SIGMAR1NPC1RAB9A
SCHEMBL20075957 0.97 SIGMAR1 (0.46) EPHX1SMN1; SMN2SIGMAR1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 822 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113831875-B Insulating adhesive film and preparation method and application thereof 深圳市纽菲斯新材料科技有限公司 2024-01-09 CN claimed
CN-114181652-B Insulating adhesive film with low dielectric loss and preparation method and application thereof 深圳市纽菲斯新材料科技有限公司 2024-01-09 CN claimed
CN-115341296-A Wear-resistant fiber for clothing and preparation method of fabric of wear-resistant fiber 创姿服饰(上海)有限公司 2022-11-15 CN claimed
CN-114181652-A Low-dielectric-loss insulating adhesive film and preparation method and application thereof 深圳市纽菲斯新材料科技有限公司 2022-03-15 CN claimed
CN-113831875-A Insulating adhesive film and preparation method and application thereof 深圳市纽菲斯新材料科技有限公司 2021-12-24 CN claimed
WO-2020218835-A1 NOVEL POLYIMIDE-TYPE POLYMER AND PREPARATION METHOD THEREFOR 서울대학교 산학협력단 2020-10-29 WO claimed
US-9944593-B2 Process for the synthesis of fluoralkyl sulfonate salts SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) 2018-04-17 US claimed
CN-101684083-B Guanidyl alkanoylamino substituted tetracycline derivative SHANDONG XUANZHU MEDICINE TECHNOLOGY CO LTD 2011-10-05 CN claimed
CN-101759604-A Guanidyl substitutional tetracycline derivative SHANDONG XUANZHU PHARM TECH CO 2010-06-30 CN claimed
CN-101684083-A Guanidyl alkanoylamino substituted tetracycline derivative SHANDONG XUANZHU MEDICINE TECH 2010-03-31 CN claimed
US-20050129645-A1 Hair shaping composition comprising at least one non-hydroxide imine L'OREAL 2005-06-16 US claimed
EP-1532963-A1 Composition for straightening the hair comprising at least one imine not being an hydroxide L'OREAL (FR) 2005-05-25 EP claimed
EP-1532960-A1 Hair styling composition containing a non-hydroxide imine L'OREAL (FR) 2005-05-25 EP claimed
EP-0024779-B1 DRUGS FOR USE WITH INTRAUTERINE DEVICES AND INTRAUTERINE DEVICES CONTAINING SAID DRUGS Shaw, Seth Thomas, Jr. (US) 1984-10-17 EP claimed
EP-0024780-B1 MEDICATED INTRAUTERINE DEVICES Shaw, Seth Thomas, Jr. (US) 1984-10-17 EP claimed
EP-0024781-B1 MEDICATED INTRAUTERINE DEVICES Shaw, Seth Thomas, Jr. (US) 1984-08-08 EP claimed
US-4381001-A A GUANIDINE IN POLYMER MATRIX; ANTIFERTILITY AGENTS AND ANTICOAGULANTS; SUSTAINED RELEASE SHAW JR SETH T (US) 1983-04-26 US claimed
EP-0024781-A1 Medicated intrauterine devices Shaw, Seth Thomas, Jr. (US) 1981-03-11 EP claimed
EP-0024780-A1 Medicated intrauterine devices Shaw, Seth Thomas, Jr. (US) 1981-03-11 EP claimed
EP-0024779-A1 Drugs for use with intrauterine devices and intrauterine devices containing said drugs Shaw, Seth Thomas, Jr. (US) 1981-03-11 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050129645-A1 Hair shaping composition comprising at least one non-hydroxide imine KRT18, INHA, H1-5 EPHX1 2359/4885SMN1; SMN2 3508/4885SIGMAR1 2720/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.