Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.31 |
| ▸ | DCK | P27707 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1065338 | 0.75 | FGFR1 (0.35) | FGFR1SLC22A6LMNATHRBMTOR | |
| SCHEMBL6855554 | 0.74 | FGFR1 (0.34) | FGFR1SLC22A6LMNATHRBMTOR | |
| SCHEMBL21237584 | 0.73 | FGFR1 (0.32) | FGFR1SLC22A6 | |
| SCHEMBL27503114 | 0.72 | FGFR1 (0.35) | FGFR1SLC22A6LMNATHRBMTOR | |
| SCHEMBL440453 | 0.70 | PDE3A (0.35) | FGFR1SLC22A6LMNATHRBMTOR | |
| SCHEMBL14125693 | 0.70 | FGFR1 (0.35) | FGFR1SLC22A6LMNATHRBMTOR | |
| SCHEMBL21230515 | 0.70 | FGFR1 (0.32) | FGFR1SLC22A6 | |
| SCHEMBL176469 | 0.69 | FGFR1 (0.34) | FGFR1SLC22A6LMNATHRBMTOR | |
| SCHEMBL28515026 | 0.69 | FGFR1 (0.34) | FGFR1SLC22A6LMNATHRBMTOR | |
| SCHEMBL784164 | 0.68 | ADORA2A (0.36) | FGFR1SLC22A6LMNATHRBMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019152955-A9 | SMALL MOLECULE DRUG CONJUGATES OF GEMCITABINE MONOPHOSPHATE | EVERETT STEVEN ALBERT (US) | 2020-08-13 | — | — | WO | disclosed |