SCHEMBL22336301

SCHEMBL22336301

CCCC[n+]1ccc(C(=O)O)cn1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR3 P49019 7/20 0.43
MEN1 O00255 1/20 0.40
APAF1 O14727 1/20 0.40
RGS12 O14924 1/20 0.40
HSP90AA1 P07900 1/20 0.40
MAPK1 P28482 1/20 0.40
KMT2A Q03164 1/20 0.40
RARB P10826 4/20 0.38
MAPT P10636 1/20 0.38
ALDH1A1 P00352 1/20 0.38
HCAR2 Q8TDS4 1/20 0.38
TP53 P04637 1/20 0.37
TSHR P16473 1/20 0.37
NPC1 O15118 1/20 0.37
NFKB1 P19838 1/20 0.37
RAB9A P51151 1/20 0.37
NFKB2 Q00653 1/20 0.37
RELA Q04206 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
PLA2G4B P0C869 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL22322538 0.98 HCAR3 (0.42) HCAR3MEN1APAF1RGS12HSP90AA1
SCHEMBL22336373 0.94 MEN1 (0.48) HCAR3MEN1APAF1RGS12HSP90AA1
SCHEMBL22322537 0.86 HSP90AA1 (0.39) HCAR3MEN1APAF1RGS12HSP90AA1
SCHEMBL22336340 0.83 MAPK1 (0.41) MEN1APAF1RGS12HSP90AA1MAPK1
Iodide SCHEMBL22322903 0.82 MAPK1 (0.40) MEN1APAF1RGS12HSP90AA1MAPK1
SCHEMBL22336368 0.80 P4HTM (0.36) HCAR3MAPTALDH1A1HCAR2TP53
SCHEMBL22336268 0.79 HCAR3 (0.44) HCAR3MAPTALDH1A1HCAR2
Hydrochloric Acid SCHEMBL22322580 0.79 HCAR2 (0.39) HCAR3MAPTALDH1A1HCAR2TSHR
SCHEMBL22336366 0.77 HCAR3 (0.37) HCAR3KMT2AMAPTALDH1A1HCAR2
SCHEMBL28336413 0.75 MEN1 (0.59) MEN1APAF1RGS12HSP90AA1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020161248-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2020-08-13 WO disclosed