Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ADH1B | P00325 | 1/20 | 0.41 |
| ▸ | ADH1C | P00326 | 1/20 | 0.41 |
| ▸ | ADH1A | P07327 | 1/20 | 0.41 |
| ▸ | ADH7 | P40394 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 4/20 | 0.39 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9814881 | 0.90 | GAA (0.53) | GAATSHRALDH1A1EPHX1ALOX15 | |
| SCHEMBL17875398 | 0.85 | — | — | |
| SCHEMBL13438529 | 0.84 | CYP2C19 (0.50) | GAATSHRALDH1A1TDP1PAOX | |
| SCHEMBL19621247 | 0.84 | GAA (0.48) | GAATSHRALDH1A1EPHX1ALOX15 | |
| SCHEMBL4784976 | 0.83 | ALDH1A1 (0.57) | GAATSHRALDH1A1EPHX1ADH1B | |
| SCHEMBL22057180 | 0.80 | MEN1 (0.37) | GAATSHRALDH1A1EPHX1TDP1 | |
| SCHEMBL27350172 | 0.80 | MAPT (0.42) | GAAEPHX1PAOX | |
| SCHEMBL31092895 | 0.79 | GAA (0.48) | GAATSHRALDH1A1EPHX1ALOX15 | |
| SCHEMBL9940233 | 0.79 | TSHR (0.46) | GAATSHRALDH1A1EPHX1ALOX15 | |
| SCHEMBL2735586 | 0.79 | TDP1 (0.56) | GAATSHRALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183437-A1 | TEAD INHIBITORS AND METHODS OF USE | SPOROS BIODISCOVERY, INC. (US) | 2023-09-28 | — | — | WO | disclosed |
| WO-2020162873-A1 | TEXTILE PRINTING | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2020-08-13 | — | — | WO | disclosed |