Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K11 | Q16584 | 7/20 | 1.00 |
| ▸ | MAP3K9 | P80192 | 2/20 | 1.00 |
| ▸ | TNIK | Q9UKE5 | 14/20 | 0.69 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.59 |
| ▸ | IKBKB | O14920 | 2/20 | 0.58 |
| ▸ | CHUK | O15111 | 2/20 | 0.58 |
| ▸ | ABL1 | P00519 | 2/20 | 0.58 |
| ▸ | INSR | P06213 | 2/20 | 0.58 |
| ▸ | CDK2 | P24941 | 2/20 | 0.58 |
| ▸ | FLT3 | P36888 | 2/20 | 0.58 |
| ▸ | SGK1 | O00141 | 1/20 | 0.58 |
| ▸ | AURKA | O14965 | 1/20 | 0.58 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.58 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.58 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.58 |
| ▸ | LCK | P06239 | 1/20 | 0.58 |
| ▸ | CDK1 | P06493 | 1/20 | 0.58 |
| ▸ | IGF1R | P08069 | 1/20 | 0.58 |
| ▸ | MET | P08581 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22971583 | 0.91 | MAP3K11 (0.83) | MAP3K11MAP3K9TNIKMAP4K1IKBKB | |
| SCHEMBL22336562 | 0.90 | MAP3K11 (0.82) | MAP3K11MAP3K9TNIKMAP4K1IKBKB | |
| SCHEMBL22336543 | 0.88 | MAP3K11 (0.79) | MAP3K11MAP3K9TNIKMAP4K1IKBKB | |
| SCHEMBL22336737 | 0.87 | MAP3K11 (0.78) | MAP3K11MAP3K9TNIKMAP4K1IKBKB | |
| SCHEMBL24535333 | 0.86 | MAP3K11 (0.75) | MAP3K11MAP3K9TNIKMAP4K1IKBKB | |
| SCHEMBL24535330 | 0.86 | MAP3K11 (0.75) | MAP3K11MAP3K9TNIKMAP4K1IKBKB | |
| SCHEMBL24535484 | 0.86 | MAP3K11 (0.75) | MAP3K11MAP3K9TNIKMAP4K1IKBKB | |
| SCHEMBL22971655 | 0.85 | MAP3K11 (0.75) | MAP3K11MAP3K9TNIKMAP4K1SGK1 | |
| SCHEMBL25083208 | 0.85 | MAP3K11 (0.73) | MAP3K11MAP3K9TNIKMAP4K1SGK1 | |
| SCHEMBL24535576 | 0.84 | MAP3K11 (0.72) | MAP3K11MAP3K9TNIKMAP4K1IKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230063768-A1 | IMMUNOPHILIN BINDING AGENTS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-03-02 | — | — | US | disclosed |
| US-20220193242-A1 | IMMUNOPHILIN-DEPENDENT INHIBITORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2022-06-23 | — | — | US | disclosed |
| US-20210040091-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR SUPPRESSING TOXIC ENDOPLASMIC RETICULUM STRESS | UNITED STATES GOVERNMENT | 2021-02-11 | — | — | US | disclosed |
| WO-2020163598-A1 | IMMUNOPHILIN-DEPENDENT INHIBITORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-08-13 | — | — | WO | disclosed |
| WO-2020163594-A1 | IMMUNOPHILIN BINDING AGENTS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-08-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220193242-A1 | IMMUNOPHILIN-DEPENDENT INHIBITORS AND USES THEREOF | CD74, CD2BP2, SERPINB1 | MAP3K11 4347/4885MAP3K9 3908/4885TNIK 824/4885 |
| US-20210040091-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR SUPPRESSING TOXIC ENDOPLASMIC RETICULUM STRESS | HSPA5, ATP2A1, DNAJC10 | MAP3K11 3182/4885MAP3K9 3319/4885TNIK 2690/4885 |
| US-20230063768-A1 | IMMUNOPHILIN BINDING AGENTS AND USES THEREOF | PMP22, MAG, FABP7 | MAP3K11 4728/4885MAP3K9 4650/4885TNIK 2864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.