Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KB | Q9UBF8 | 7/20 | 0.58 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.57 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.56 |
| ▸ | PIK3C2G | O75747 | 3/20 | 0.56 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CFTR | P13569 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | PI4KA | P42356 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22336886 | 0.87 | PIK3CD (0.55) | PI4KBPIK3CDPIK3CGPIK3C2GPIK3CA | |
| SCHEMBL22338386 | 0.86 | PIK3CD (0.59) | PI4KBPIK3CDPIK3CGPIK3C2GPIK3CA | |
| SCHEMBL22336718 | 0.86 | PIK3CD (0.56) | PI4KBPIK3CDPIK3CGPIK3C2GPIK3CA | |
| SCHEMBL22336673 | 0.85 | PIK3CD (0.67) | PI4KBPIK3CDPIK3CGPIK3C2GPIK3CA | |
| SCHEMBL22336540 | 0.85 | PIK3CD (0.54) | PI4KBPIK3CDPIK3CGPIK3C2GPIK3CA | |
| SCHEMBL22336688 | 0.82 | PI4KB (0.55) | PI4KBPIK3CDPIK3CGPIK3C2GPIK3CA | |
| SCHEMBL22336557 | 0.81 | PIK3CD (0.51) | PI4KBPIK3CDPIK3CGPIK3C2GPIK3CA | |
| SCHEMBL22338451 | 0.80 | PIK3CD (0.74) | PI4KBPIK3CDPIK3CGPIK3C2GPIK3CA | |
| SCHEMBL22336563 | 0.77 | PI4KB (0.74) | PI4KBPIK3CDPIK3CGPIK3C2GPIK3CA | |
| SCHEMBL24535632 | 0.77 | PIK3CD (0.78) | PI4KBPIK3CDPIK3CGPIK3C2GPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020163598-A1 | IMMUNOPHILIN-DEPENDENT INHIBITORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-08-13 | — | — | WO | disclosed |