SCHEMBL2233679

SCHEMBL2233679

Clc1cc(Cl)cc(-c2ccccc2Cl)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.61
PTPRC P08575 1/20 0.46
MAOB P27338 2/20 0.44
TSHR P16473 3/20 0.43
LMNA P02545 1/20 0.43
RORB Q92753 1/20 0.42
BACE1 P56817 1/20 0.42
TRPA1 O75762 1/20 0.42
NPC1 O15118 2/20 0.41
TP53 P04637 2/20 0.41
RAB9A P51151 2/20 0.41
HPGD P15428 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
AHR P35869 1/20 0.41
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.41
NFKB1 P19838 1/20 0.41
CASP3 P42574 1/20 0.41
NFKB2 Q00653 1/20 0.41
RELA Q04206 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29586653 1.00 CYP2A6 (0.61) CYP2A6PTPRCMAOBTSHRLMNA
SCHEMBL9762462 0.87 CYP2A6 (0.70) CYP2A6MAOBTSHRLMNABACE1
SCHEMBL11296979 0.82 AHR (0.46) CYP2A6TSHRRORBBACE1TRPA1
SCHEMBL4456479 0.81 AHR (0.45) CYP2A6PTPRCTSHRRORBAHR
SCHEMBL29464821 0.81 CYP2A6 (0.62) CYP2A6MAOBTSHRRORBBACE1
SCHEMBL1520883 0.81 CYP2A6 (0.62) CYP2A6MAOBTSHRRORBBACE1
SCHEMBL4454427 0.80 CYP2A6 (0.61) CYP2A6MAOBTSHRLMNABACE1
SCHEMBL30505263 0.80 CYP2A6 (0.61) CYP2A6MAOBTSHRLMNABACE1
SCHEMBL9479255 0.77 CYP2A6 (0.71) CYP2A6MAOBTSHRLMNABACE1
SCHEMBL4450486 0.77 CYP2A6 (0.50) CYP2A6TSHRLMNANPC1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP claimed
US-7989194-B2 PCB-degrading recombinant bacterium, product for the bioremediation and method of bioremediation UNIVERSIDAD TECNICA FEDERICO SANTA MARIA (CL) 2011-08-02 US claimed
US-20080318302-A1 PCB-Degrading recombinant bacterium, product for the bioremediation and method of bioremediation UNIVERSIDAD TECNICA FEDERICO SANTA MARIA (CL) 2008-12-25 US claimed
CN-115850021-A Preparation method of polychlorinated biphenyl standard substance 上海安谱实验科技股份有限公司 2023-03-28 CN disclosed
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP disclosed
US-7989194-B2 PCB-degrading recombinant bacterium, product for the bioremediation and method of bioremediation UNIVERSIDAD TECNICA FEDERICO SANTA MARIA (CL) 2011-08-02 US disclosed
US-20090269857-A1 Instruments for detecting low-molecular weight substance FUJIKURA KASEI CO., LTD. (JP) 2009-10-29 US disclosed
US-20080318302-A1 PCB-Degrading recombinant bacterium, product for the bioremediation and method of bioremediation UNIVERSIDAD TECNICA FEDERICO SANTA MARIA (CL) 2008-12-25 US disclosed
US-20050148097-A1 Instruments for detecting low-molecular weight substance ENBIOTEC LABORATORIES C., LTD. (JP) 2005-07-07 US disclosed
EP-1489420-A1 INSTRUMENTS FOR DETECTING LOW-MOLECULAR WEIGHT SUBSTANCE Enbiotec Laboratories Co., Ltd. (JP) 2004-12-22 EP disclosed
US-5403477-A Sample preparation extractor comprising composite tube of polyolefin or fluoropolymer having on interior wall carbon allotrope particles to which contaminants adhere until removed by solvent; gas or liquid chromatography THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1995-04-04 US disclosed
US-5389251-A Organic contaminant separator THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1995-02-14 US disclosed
US-5308493-A Sampling and analyzing impurities in polymer composite tubes and passing solvents, analyzing with chromatography THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1994-05-03 US disclosed
US-5273655-A Passing a contaminated aqueous medium through a tube of a blend of polyolefin and polyester; dissolving the adhering impurities and chromatographically analyzing THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1993-12-28 US disclosed
US-5037553-A Adhesion to polyolefin tube; solvent removal; chromatographic analysis THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) 1991-08-06 US disclosed
US-4276179-A Removing halogenated hydrocarbons from aqueous media by utilizing a polyolefinic microporous adsorbent CELANESE CORPORATION (US) 1981-06-30 US disclosed
US-4246255-A Disposal of PCB ROCKWELL INTERNATIONAL CORPORATION (US) 1981-01-20 US disclosed