SCHEMBL4450486

SCHEMBL4450486

Clc1cc(Cl)c(-c2ccccc2Cl)c(Cl)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.50
LMNA P02545 2/20 0.45
TSHR P16473 2/20 0.45
NPC1 O15118 3/20 0.43
RAB9A P51151 3/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
TP53 P04637 2/20 0.43
HPGD P15428 1/20 0.43
PDK2 Q15119 1/20 0.43
DPP4 P27487 1/20 0.41
ALDH1A1 P00352 3/20 0.41
PLA2G7 Q13093 1/20 0.41
HSD11B1 P28845 1/20 0.40
HSP90AA1 P07900 1/20 0.39
HSP90AB1 P08238 1/20 0.39
GRIN2D O15399 1/20 0.39
GRIN3B O60391 1/20 0.39
GRIN1 Q05586 1/20 0.39
GRIN2A Q12879 1/20 0.39
GRIN2B Q13224 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29387186 1.00 CYP2A6 (0.50) CYP2A6LMNATSHRNPC1RAB9A
SCHEMBL2469822 0.83 CYP2A6 (0.55) CYP2A6LMNATSHRNPC1RAB9A
SCHEMBL4456481 0.80 ALDH1A1 (0.43) TSHRPDK2ALDH1A1HSP90AA1IDO1
SCHEMBL2094837 0.78 PDK2 (0.40) CYP2A6LMNATSHRTP53PDK2
SCHEMBL4225498 0.78 ALDH1A1 (0.48) LMNATSHRNPC1RAB9ASMN1; SMN2
SCHEMBL4453386 0.78 CYP2A6 (0.44) CYP2A6LMNATSHRNPC1RAB9A
SCHEMBL30621943 0.78 CYP2A6 (0.44) CYP2A6LMNATSHRNPC1RAB9A
SCHEMBL29765253 0.78 ALDH1A1 (0.48) CYP2A6LMNATSHRNPC1RAB9A
SCHEMBL21620288 0.78 CYP1A2 (0.46) TSHRNPC1RAB9ASMN1; SMN2HPGD
SCHEMBL4453348 0.78 ALDH1A1 (0.48) CYP2A6LMNATSHRNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP claimed
CN-117147725-B Method for measuring polychlorinated biphenyl content and total amount in sample by adopting quantitative ion abundance compensation mode 四川省生态环境监测总站 2024-04-26 CN disclosed
CN-117147725-A Method for measuring polychlorinated biphenyl content and total amount in sample by adopting quantitative ion abundance compensation mode 四川省生态环境监测总站 2023-12-01 CN disclosed
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP disclosed
US-20090269857-A1 Instruments for detecting low-molecular weight substance FUJIKURA KASEI CO., LTD. (JP) 2009-10-29 US disclosed
US-20050148097-A1 Instruments for detecting low-molecular weight substance ENBIOTEC LABORATORIES C., LTD. (JP) 2005-07-07 US disclosed
EP-1489420-A1 INSTRUMENTS FOR DETECTING LOW-MOLECULAR WEIGHT SUBSTANCE Enbiotec Laboratories Co., Ltd. (JP) 2004-12-22 EP disclosed
US-5970804-A Methods and apparatus for analysis of complex mixtures TRUSTEES OF TUFTS COLLEGE (US) 1999-10-26 US disclosed
EP-0895584-A1 ANALYSIS OF COMPLEX MIXTURES TRUSTEES OF TUFTS COLLEGE (US) 1999-02-10 EP disclosed
WO-1997041412-A1 ANALYSIS OF COMPLEX MIXTURES TRUSTEES OF TUFTS COLLEGE (US) 1997-11-06 WO disclosed
WO-1997041419-A1 ANALYSIS OF COMPLEX MIXTURES TRUSTEES OF TUFTS COLLEGE (US) 1997-11-06 WO disclosed
US-5668373-A FOR DETERMINING PRESENCE/ABSENCE OF A SPECIFIC CONSTITUENT IN A MIXTURE TRUSTEES OF TUFTS COLLEGE (US) 1997-09-16 US disclosed