SCHEMBL22337131

SCHEMBL22337131

Brc1ccc2c(c1)Oc1c(ccc3ccccc13)C21c2ccccc2-c2ccccc21

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
AHR P35869 2/20 0.35
CYP2A6 P11509 1/20 0.34
PDK2 Q15119 1/20 0.34
ALDH1A1 P00352 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
HPGD P15428 1/20 0.32
CYP2C19 P33261 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30803800 0.91 PDK2 (0.37) AHRCYP2A6PDK2ALDH1A1CYP1A2
SCHEMBL23273215 0.91 PDK2 (0.37) AHRCYP2A6PDK2ALDH1A1CYP1A2
SCHEMBL20222338 0.91 AHR (0.33) AHRCYP2A6PDK2ALDH1A1CYP1A2
SCHEMBL22337257 0.91 PDK2 (0.36) AHRCYP2A6PDK2ALDH1A1CYP1A2
SCHEMBL20222319 0.90 PDK2 (0.36) AHRCYP2A6PDK2ALDH1A1CYP1A2
SCHEMBL20926273 0.89 CYP2A6 (0.36) AHRCYP2A6PDK2ALDH1A1CYP1A2
SCHEMBL20222320 0.89 PDK2 (0.37) AHRCYP2A6PDK2ALDH1A1CYP1A2
SCHEMBL20926267 0.88 PDK2 (0.40) CYP2A6PDK2ALDH1A1CYP1A2CYP2D6
SCHEMBL23307309 0.86 ALDH1A1 (0.33) CYP2A6ALDH1A1CYP1A2CYP2C9HPGD
SCHEMBL25883223 0.84 PDK2 (0.36) AHRCYP2A6PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020162703-A1 NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME 주식회사 엘지화학 2020-08-13 WO disclosed