Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 3/20 | 0.36 |
| ▸ | NOS2 | P35228 | 3/20 | 0.36 |
| ▸ | NOS1 | P29475 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18542965 | 0.96 | HTR2A (0.38) | HTR2AHTR2CHTR2BALDH1A1POLB | |
| SCHEMBL18629743 | 0.81 | HTR2C (0.40) | HTR2AHTR2CHTR2BPOLBTSHR | |
| SCHEMBL31321403 | 0.80 | MEN1 (0.46) | HTR2AHTR2CHTR2BMAPTSMN1; SMN2 | |
| SCHEMBL13641224 | 0.78 | HTR2A (0.33) | HTR2AHTR2CHTR2BNOS3NOS2 | |
| SCHEMBL24469681 | 0.77 | CHRNE (0.40) | TSHRL3MBTL1NOS3NOS2NOS1 | |
| SCHEMBL21923213 | 0.77 | HTR2C (0.42) | HTR2AHTR2CHTR2BALDH1A1NOS3 | |
| SCHEMBL11017100 | 0.77 | NOS3 (0.33) | ALDH1A1TSHRMAPK1NOS3NOS2 | |
| SCHEMBL10286088 | 0.77 | HTR2A (0.35) | HTR2AHTR2CHTR2BALDH1A1TSHR | |
| SCHEMBL795349 | 0.75 | NOS3 (0.44) | HTR2AHTR2CHTR2BNOS3NOS2 | |
| SCHEMBL20661751 | 0.75 | HTR2C (0.43) | HTR2AHTR2CHTR2BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020163193-A1 | BICYCLIC ETHER O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLUCOPYRANOSIDASE INHIBITORS | BIOGEN MA INC. (US) | 2020-08-13 | — | — | WO | disclosed |