Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | CACNB4 | O00305 | 2/20 | 0.33 |
| ▸ | CACNA1A | O00555 | 2/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.33 |
| ▸ | CACNG3 | O60359 | 2/20 | 0.33 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.33 |
| ▸ | CACNB3 | P54284 | 2/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.33 |
| ▸ | CACNG7 | P62955 | 2/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.33 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.33 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.33 |
| ▸ | CACNG1 | Q06432 | 2/20 | 0.33 |
| ▸ | CACNB2 | Q08289 | 2/20 | 0.33 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.33 |
| ▸ | CACNA1E | Q15878 | 2/20 | 0.33 |
| ▸ | CACNA2D4 | Q7Z3S7 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29496515 | 0.86 | GPR119 (0.44) | GPR119PIK3CDDGAT1GRM5 | |
| SCHEMBL31128772 | 0.83 | PIK3CD (0.45) | GPR119PIK3CDCACNB4CACNA1ACACNA1G | |
| SCHEMBL31051492 | 0.83 | PIK3CD (0.45) | GPR119PIK3CDCACNB4CACNA1ACACNA1G | |
| SCHEMBL22337416 | 0.78 | PIK3CD (0.44) | GPR119PIK3CDDGAT1HDAC1 | |
| SCHEMBL22337417 | 0.78 | PIK3CD (0.44) | GPR119PIK3CDDGAT1HDAC1 | |
| SCHEMBL23377679 | 0.75 | PIK3CD (0.49) | GPR119PIK3CD | |
| SCHEMBL21665749 | 0.74 | GPR119 (0.67) | GPR119PIK3CD | |
| SCHEMBL30938143 | 0.74 | GPR119 (0.67) | GPR119PIK3CD | |
| SCHEMBL23377710 | 0.74 | HCRTR1 (0.47) | GPR119PIK3CDDGAT1 | |
| SCHEMBL23377549 | 0.74 | PIK3CD (0.46) | GPR119PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020163193-A1 | BICYCLIC ETHER O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLUCOPYRANOSIDASE INHIBITORS | BIOGEN MA INC. (US) | 2020-08-13 | — | — | WO | disclosed |