Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 18/20 | 0.80 |
| ▸ | FBP1 | P09467 | 2/20 | 0.78 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.78 |
| ▸ | KDR | P35968 | 2/20 | 0.78 |
| ▸ | AURKA | O14965 | 1/20 | 0.78 |
| ▸ | INSR | P06213 | 1/20 | 0.78 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.78 |
| ▸ | FLT4 | P35916 | 1/20 | 0.78 |
| ▸ | CLK1 | P49759 | 1/20 | 0.78 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.78 |
| ▸ | TEK | Q02763 | 1/20 | 0.78 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.78 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.77 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.77 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.77 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.77 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.77 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.77 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.77 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22336875 | 0.95 | EGFR (0.87) | EGFRFBP1ERBB2KDRAURKA | |
| SCHEMBL24535320 | 0.94 | EGFR (0.72) | EGFRFBP1ERBB2KDRAURKA | |
| SCHEMBL25083284 | 0.93 | EGFR (0.71) | EGFRFBP1ERBB2KDRAURKA | |
| SCHEMBL6994526 | 0.92 | EGFR (0.69) | EGFRFBP1ERBB2KDRAURKA | |
| SCHEMBL8211574 | 0.90 | HDAC3 (0.89) | EGFRERBB2KDRHDAC3HDAC4 | |
| SCHEMBL10118455 | 0.90 | HDAC3 (0.83) | EGFRERBB2KDRHDAC3HDAC4 | |
| SCHEMBL30520472 | 0.89 | EGFR (0.87) | EGFRFBP1ERBB2KDRAURKA | |
| SCHEMBL13524614 | 0.89 | EGFR (0.87) | EGFRFBP1ERBB2KDRAURKA | |
| SCHEMBL8205069 | 0.89 | HDAC3 (0.93) | EGFRERBB2KDRHDAC3HDAC4 | |
| SCHEMBL12694355 | 0.89 | KDR (0.71) | EGFRFBP1ERBB2KDRHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230063768-A1 | IMMUNOPHILIN BINDING AGENTS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-03-02 | — | — | US | disclosed |
| WO-2020163594-A1 | IMMUNOPHILIN BINDING AGENTS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-08-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230063768-A1 | IMMUNOPHILIN BINDING AGENTS AND USES THEREOF | PMP22, MAG, FABP7 | EGFR 3726/4885FBP1 1888/4885ERBB2 3924/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.