Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20017286 | 0.84 | EPHX1 (0.52) | EPHX1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL19172100 | 0.81 | EPHX1 (0.62) | EPHX1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL5019737 | 0.80 | POLB (0.48) | EPHX1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL26431375 | 0.75 | ALDH1A1 (0.38) | EPHX1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL19171555 | 0.75 | MEN1 (0.46) | EPHX1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL19703744 | 0.74 | EPHX1 (0.53) | EPHX1SMN1; SMN2ALDH1A1MEN1LMNA | |
| SCHEMBL2625566 | 0.74 | EPHX1 (0.48) | EPHX1RAB9AALDH1A1MEN1LMNA | |
| SCHEMBL13644760 | 0.74 | NPC1 (0.50) | EPHX1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL19171338 | 0.73 | NPC1 (0.57) | EPHX1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL21676411 | 0.72 | ALDH1A1 (0.39) | EPHX1NPC1RAB9AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200255416-A1 | BAF Complex Modulating Compounds and Methods of Using the Same | THE BOARD OF TRUSTEES OF LELAND STANFORD JUNIOR UNIVERSITY | 2020-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200255416-A1 | BAF Complex Modulating Compounds and Methods of Using the Same | SMARCC1, SMARCC2, ATRIP | EPHX1 3816/4885NPC1 3450/4885RAB9A 1321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.