Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 2/20 | 0.56 |
| ▸ | KDR | P35968 | 12/20 | 0.54 |
| ▸ | EGFR | P00533 | 11/20 | 0.54 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.51 |
| ▸ | LCK | P06239 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.48 |
| ▸ | FLT1 | P17948 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24353219 | 0.86 | EGFR (0.55) | KDREGFRHDAC3HDAC1HDAC6 | |
| SCHEMBL24938199 | 0.77 | EGFR (0.52) | KDREGFRHDAC3HDAC1HDAC6 | |
| SCHEMBL13299050 | 0.75 | ENPP1 (0.86) | SRCKDREGFRENPP1HDAC3 | |
| SCHEMBL8649615 | 0.75 | ENPP1 (0.86) | SRCKDREGFRENPP1HDAC3 | |
| SCHEMBL24166697 | 0.75 | KDR (0.70) | SRCKDREGFRHDAC3HDAC4 | |
| SCHEMBL23075114 | 0.73 | KDR (0.69) | SRCKDREGFR | |
| SCHEMBL20614884 | 0.72 | SRC (0.41) | SRCKDREGFRLCKFLT1 | |
| SCHEMBL20614661 | 0.72 | SRC (0.41) | SRCKDREGFRLCK | |
| SCHEMBL7402352 | 0.71 | KDR (0.64) | SRCKDREGFRFLT1 | |
| SCHEMBL8258194 | 0.71 | EGFR (0.83) | SRCKDREGFRLCKHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020163594-A1 | IMMUNOPHILIN BINDING AGENTS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-08-13 | — | — | WO | disclosed |