Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.33 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.33 |
| ▸ | TLR4 | O00206 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22323036 | 1.00 | MAPT (0.39) | MAPTGAAPKMHTTALDH1A1 | |
| SCHEMBL22216464 | 0.90 | MAPT (0.40) | MAPTGAAPKMHTTALDH1A1 | |
| SCHEMBL22322985 | 0.86 | MAPT (0.36) | MAPTGAAPKMHTTALDH1A1 | |
| SCHEMBL3367604 | 0.84 | ALDH1A1 (0.39) | MAPTGAAPKMALDH1A1MEN1 | |
| SCHEMBL8394031 | 0.79 | ALDH1A1 (0.38) | MAPTPKMALDH1A1MEN1KMT2A | |
| SCHEMBL23907332 | 0.78 | MAPT (0.51) | MAPTGAAPKMHTTALDH1A1 | |
| SCHEMBL16931294 | 0.78 | NPSR1 (0.36) | MAPTALDH1A1MEN1KMT2ATLR4 | |
| SCHEMBL16931293 | 0.78 | NPSR1 (0.36) | MAPTALDH1A1MEN1KMT2ATLR4 | |
| SCHEMBL22206975 | 0.78 | ALDH1A1 (0.39) | MAPTGAAHTTALDH1A1HSD17B10 | |
| SCHEMBL22207029 | 0.77 | MAPT (0.50) | MAPTGAAPKMHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020161257-A1 | 3-AMINO-2-[2-(ACYLAMINO)PYRIDIN-4-YL]-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE AS CSNK1 INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2020-08-13 | — | — | WO | disclosed |