SCHEMBL22338446

SCHEMBL22338446

C1=C(c2ccc(N(c3ccc(-c4ccccc4)cc3)c3ccc(-c4ccccc4)cc3)cc2)c2cccc3cccc1c23

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 3/20 0.41
PTPN1 P18031 2/20 0.41
MAPT P10636 2/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
PTPRC P08575 2/20 0.37
PTPRF P10586 1/20 0.37
CDC25B P30305 1/20 0.37
PDE6D O43924 1/20 0.35
PTAFR P25105 1/20 0.34
BACE1 P56817 4/20 0.33
ALDH1A1 P00352 4/20 0.33
TSHR P16473 2/20 0.33
HSD17B10 Q99714 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
HSD17B3 P37058 1/20 0.33
ATM Q13315 1/20 0.33
S100A4 P26447 1/20 0.32
CYP3A4 P08684 2/20 0.32
CASP1 P29466 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4560752 0.87 MAPK1 (0.52) MAPK1PTPN1MAPTMEN1KMT2A
SCHEMBL22338411 0.84 PTPN1 (0.35) MAPK1PTPN1MAPTMEN1KMT2A
SCHEMBL22338755 0.83 MEN1 (0.33) MAPK1PTPN1MAPTMEN1KMT2A
SCHEMBL18943695 0.82 MAPT (0.33) MAPK1MAPTMEN1KMT2APTAFR
SCHEMBL22338525 0.81 PTPN1 (0.36) PTPN1PTPRCPTPRFCDC25BHSD17B3
SCHEMBL22338403 0.80 PTPN1 (0.36) MAPK1PTPN1MAPTPTPRCPTPRF
SCHEMBL24944469 0.79 ALDH1A1 (0.46) MAPK1MAPTPDE6DALDH1A1TSHR
SCHEMBL24945437 0.79 ALDH1A1 (0.46) MAPK1MAPTPDE6DALDH1A1TSHR
SCHEMBL21206198 0.79 ALDH1A1 (0.46) MAPK1MAPTPDE6DALDH1A1TSHR
SCHEMBL25972651 0.79 ALDH1A1 (0.46) MAPK1MAPTPDE6DALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12022733-B2 Organic electroluminescence device and monoamine compound for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2024-06-25 US disclosed
US-12022733-B2 Organic electroluminescence device and monoamine compound for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2024-06-25 US disclosed
US-20230137318-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND MONOAMINE COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-04 US disclosed
US-20230137318-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND MONOAMINE COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-04 US disclosed
US-20200259104-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND MONOAMINE COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2020-08-13 US disclosed