Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2228431 | 1.00 | MMP2 (0.48) | MMP2MMP9GRIN2BRAB9AMAPT | |
| SCHEMBL2228428 | 1.00 | MMP2 (0.48) | MMP2MMP9GRIN2BRAB9AMAPT | |
| SCHEMBL2227124 | 0.89 | MMP2 (0.44) | MMP2MMP9GRIN2BRAB9AMAPT | |
| SCHEMBL2228626 | 0.87 | GRIN2B (0.48) | MMP2MMP9GRIN2BRAB9AMAPT | |
| SCHEMBL2286420 | 0.83 | GRIN2B (0.43) | MMP2MMP9GRIN2BMAPTMEN1 | |
| Trifluoroacetic Acid SCHEMBL2287813 | 0.82 | GRIN2B (0.47) | MMP2MMP9GRIN2BRAB9AMAPT | |
| SCHEMBL2228696 | 0.81 | MMP2 (0.48) | MMP2MMP9GRIN2BRAB9AMAPT | |
| SCHEMBL2227752 | 0.81 | GRIN2B (0.44) | MMP2MMP9GRIN2BMAPTALDH1A1 | |
| SCHEMBL2229355 | 0.80 | GRIN2B (0.42) | MMP2MMP9GRIN2BKCNA5 | |
| SCHEMBL2227267 | 0.78 | GRIN2B (0.44) | MMP2MMP9GRIN2BRAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011089550-A1 | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI AVENTIS (FR) | 2011-07-28 | — | — | WO | claimed |
| WO-2011089550-A1 | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI AVENTIS (FR) | 2011-07-28 | — | — | WO | disclosed |