Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 8/20 | 0.47 |
| ▸ | QDPR | P09417 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | KHK | P50053 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24109238 | 0.87 | SPHK1 (0.42) | — | |
| SCHEMBL8341441 | 0.81 | NOS3 (0.43) | HTR2C | |
| SCHEMBL14996644 | 0.80 | ESR2 (0.53) | — | |
| SCHEMBL14996645 | 0.80 | ESR2 (0.53) | — | |
| Enefexine SCHEMBL499360 | 0.79 | SLC18A3 (0.55) | SLC18A3SIGMAR1HTR2CQDPRHTR3A | |
| Enefexine SCHEMBL4886231 | 0.78 | SLC18A3 (0.53) | SLC18A3SIGMAR1HTR2CQDPRHTR3A | |
| SCHEMBL14996691 | 0.77 | SPHK1 (0.40) | — | |
| SCHEMBL14996646 | 0.77 | SPHK1 (0.40) | — | |
| SCHEMBL7917964 | 0.76 | SLC18A3 (0.52) | SLC18A3SIGMAR1HTR2CQDPR | |
| SCHEMBL5584921 | 0.76 | SLC18A3 (0.55) | SLC18A3SIGMAR1HTR2CQDPRHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020163689-A1 | 20-HETE FORMATION INHIBITORS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-08-13 | — | — | WO | disclosed |