Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 4/20 | 0.49 |
| ▸ | CA2 | P00918 | 4/20 | 0.49 |
| ▸ | CA5A | P35218 | 3/20 | 0.49 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.49 |
| ▸ | MIF | P14174 | 1/20 | 0.49 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.47 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | ESRRA | P11474 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28148259 | 0.85 | ESRRA (0.56) | FLT3CA1CA2CA5ACA5B | |
| SCHEMBL30185436 | 0.85 | FLT3 (0.52) | FLT3CA1CA2CA5ACA5B | |
| SCHEMBL30185433 | 0.85 | FLT3 (0.52) | FLT3CA1CA2CA5ACA5B | |
| SCHEMBL30185429 | 0.84 | FLT3 (0.54) | FLT3CA1CA2CA5ACA5B | |
| SCHEMBL29158522 | 0.82 | CA1 (0.68) | FLT3CA1CA2CA5ACA5B | |
| SCHEMBL22643367 | 0.82 | MIF (0.46) | CA1CA2CA5ACA5BMIF | |
| SCHEMBL28319782 | 0.81 | FLT3 (0.60) | FLT3CA1CA2CA5ACA5B | |
| SCHEMBL28864474 | 0.81 | STIM1 (0.62) | CA1CA2CA5ACA5BMIF | |
| SCHEMBL30185430 | 0.80 | FLT3 (0.47) | FLT3CA1CA2CA5ACA5B | |
| SCHEMBL30185431 | 0.80 | FLT3 (0.47) | FLT3CA1CA2CA5ACA5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020163236-A1 | TREATING LONG QT SYNDROME | THE GENERAL HOSPITAL CORPORATION (US) | 2020-08-13 | — | — | WO | disclosed |
| CN-109111404-A | The preparation method of 1- aryl -4- methoxycarbonyl base -1,2,3- triazole derivatives | 昆明理工大学 | 2019-01-01 | — | — | CN | disclosed |